GNH USA

Europe — EMA

Hydroxyzine Renaudin

GNH USA supplies Hydroxyzine Renaudin (Hydroxyzine Hydrochloride), a H1 receptor antagonist for reactions, pruritus, anxiety and nausea. Request a quote.

Hydroxyzine Hydrochloride

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What is Hydroxyzine Hydrochloride?

Hydroxyzine Hydrochloride, the active ingredient in Hydroxyzine Renaudin, is a H1 receptor antagonist presented as a injectable solution for intramuscular and intravenous use. It treats allergic reactions, pruritus, anxiety, sedation, nausea and vomiting in appropriate patients.

GNH USA supplies Hydroxyzine Renaudin as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Hydroxyzine Hydrochloride used for?

Hydroxyzine Renaudin, an H1 receptor antagonist, is used to manage conditions mediated by histamine release and related central nervous system effects.

Allergic reactions: provides rapid relief of symptoms such as hives, itching and swelling. Pruritus: reduces skin itching associated with dermatologic disorders. Anxiety: produces a calming and sedative effect in patients with acute anxiety. Nausea and vomiting: helps control postoperative or chemotherapy‑induced nausea.

What are the side effects of Hydroxyzine Hydrochloride?

Hydroxyzine Renaudin may cause a range of adverse reactions, some of which are common while others are rare but serious.

Common Side Effects: - Drowsiness - Dry mouth - Blurred vision - Dizziness

Serious or Rare Side Effects: - Cardiac arrhythmia - Severe hypotension - Anaphylaxis - Hepatotoxicity - Seizures

What precautions apply to Hydroxyzine Hydrochloride?

When using Hydroxyzine Renaudin, several safety considerations should be observed. - Pregnancy: safety not established; use only if benefit outweighs risk. - Breastfeeding: drug is excreted in milk; caution advised. - Elderly: increased sensitivity to sedative effects; dose adjustment may be needed. - Concomitant CNS depressants: may enhance sedation and respiratory depression. - Renal/hepatic impairment: monitor and adjust dosage as appropriate. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Hydroxyzine Hydrochloride interact with?

Hydroxyzine Renaudin can interact with other medicines, requiring careful management.

Major Interactions (Avoid): - Alcohol: additive CNS depression. - Opioids: increased risk of respiratory depression. - Other CNS depressants (e.g., benzodiazepines): enhanced sedation. - Anticholinergic agents: may exacerbate anticholinergic side effects.

Moderate Interactions (Monitor Closely): - Other antihistamines: potential additive sedation. - MAO inhibitors: possible increased serotonergic effects. - CYP450 inhibitors: may raise hydroxyzine plasma levels.

Frequently asked questions

What is Hydroxyzine Renaudin used for?+
Hydroxyzine Renaudin is a sterile injectable formulation of hydroxyzine hydrochloride indicated for the management of acute allergic reactions, pruritus, anxiety, sedation, and nausea/vomiting in appropriate clinical settings. It is administered by intramuscular or intravenous route under medical supervision.
How does hydroxyzine work?+
Hydroxyzine works by selectively blocking peripheral H1 histamine receptors, which prevents histamine‑mediated vasodilation, increased vascular permeability and sensory nerve activation. Its additional anticholinergic, anti‑serotonergic and anti‑adrenergic actions contribute to its sedative, anxiolytic and anti‑emetic properties.
What is the usual dose of Hydroxyzine Renaudin?+
The dosage of Hydroxyzine Renaudin is determined by the prescribing clinician based on the patient’s condition, age, weight, renal and hepatic function, and the route of administration. The prescriber selects the appropriate concentration and volume for intramuscular or intravenous injection.
Is Hydroxyzine Renaudin safe in pregnancy or breastfeeding?+
Safety data for hydroxyzine during pregnancy and lactation are limited. It is classified as pregnancy category unknown, and because the drug is excreted in breast milk, it should be used only if the potential benefit justifies the potential risk to the fetus or infant. Consultation with a specialist is recommended.
How do I order Hydroxyzine Renaudin from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including cold‑chain if needed) and assists with import documentation.
How does Hydroxyzine Renaudin compare with other antihistamines?+
Compared with first‑generation oral antihistamines, Hydroxyzine Renaudin offers rapid onset via injection and higher plasma concentrations, making it suitable for acute settings. Unlike some antihistamines that lack sedative effects, hydroxyzine provides both antihistaminic and anxiolytic actions, but it may cause more pronounced drowsiness. It is not interchangeable with second‑generation antihistamines that have reduced central nervous system penetration.
What are the storage requirements for Hydroxyzine Renaudin?+
Store at 2‑8 °C: keep the vial refrigerated, protect from light, and do not freeze or shake the solution. If temporary exposure to higher temperatures occurs, return the product to controlled conditions promptly and inspect for any changes before use.
How is Hydroxyzine Renaudin administered?+
Hydroxyzine Renaudin is supplied as a sterile injectable solution for intramuscular or intravenous injection. The appropriate dose is drawn into a syringe under aseptic technique and administered by a qualified healthcare professional, observing standard infection‑control practices and monitoring the patient for any immediate reactions.
What are the most serious risks associated with Hydroxyzine Renaudin?+
Serious adverse reactions, although rare, include cardiac arrhythmias, severe hypotension, anaphylactic shock, hepatotoxicity and seizures. Patients should be monitored for signs of cardiovascular instability, respiratory depression, or allergic response, especially when combined with other central nervous system depressants.
Who should not use Hydroxyzine Renaudin?+
Contra‑indications include patients with known hypersensitivity to hydroxyzine or any component of the formulation, and individuals with severe hepatic impairment where the drug may accumulate. Caution is advised in the elderly, patients taking other sedatives, and those with a history of QT prolongation or cardiac conduction disorders.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Hydroxyzine Hydrochloride
Route
Intramuscular Use , Intravenous Use
Manufacturer
Laboratoire Renaudin
Origin
EU

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