GNH USA

Europe — EMA

Hydroxyzine Orifarm

GNH USA supplies Hydroxyzine Orifarm (Hydroxyzine Hydrochloride), an antihistamine for allergic rhinitis, urticaria and anxiety. Request a quote for supply.

Hydroxyzine Hydrochloride

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What is Hydroxyzine Hydrochloride?

Hydroxyzine Hydrochloride, the active ingredient in Hydroxyzine Orifarm, is a first‑generation antihistamine presented as an oral dosage form for oral use. It is indicated for relief of allergic symptoms, management of urticaria, and provides anxiolytic and sedative effects in appropriate clinical settings.

GNH USA supplies Hydroxyzine Orifarm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides full regulatory documentation to facilitate import, distribution and clinical use across global markets.

What is Hydroxyzine Hydrochloride used for?

Hydroxyzine Orifarm, a first‑generation antihistamine, acts on peripheral H1 receptors to alleviate allergic and related conditions.

Allergic rhinitis: relief of nasal itching, sneezing and watery discharge. Urticaria (hives): reduction of wheal formation and itching. Anxiety and tension: provides short‑term anxiolytic effect and calming. Pre‑operative or post‑operative sedation: produces sedation to facilitate surgical procedures and recovery.

What are the side effects of Hydroxyzine Hydrochloride?

Hydroxyzine Orifarm may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Drowsiness: feeling of sleepiness or reduced alertness. - Dry mouth: decreased salivation leading to oral discomfort. - Blurred vision: temporary difficulty focusing. - Constipation: slowed gastrointestinal motility.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction with airway compromise. - Cardiac arrhythmia: irregular heart rhythm that may require monitoring. - Severe hypotension: marked drop in blood pressure causing dizziness or fainting.

What precautions apply to Hydroxyzine Hydrochloride?

When prescribing Hydroxyzine Orifarm, clinicians should consider several precautionary measures to ensure safe use.

Pregnancy: safety category unknown; use only if potential benefit justifies risk. Elderly: increased sensitivity to sedation and anticholinergic effects; monitor closely. Driving: patients should avoid operating machinery until they know how the drug affects them. Concomitant CNS depressants: use with caution due to additive sedative effects. Store at room temperature: keep in original packaging, protect from moisture and light.

What does Hydroxyzine Hydrochloride interact with?

Hydroxyzine Orifarm can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): may cause severe hypotension and excessive sedation. - CNS depressants (e.g., benzodiazepines, opioids): additive central nervous system depression. - Anticholinergic drugs: heightened anticholinergic burden leading to confusion or urinary retention.

Moderate Interactions (Monitor Closely): - Alcohol: enhances drowsiness and impairment. - Antihypertensives: may potentiate blood pressure‑lowering effects. - Anticholinergic agents: monitor for increased dry mouth, constipation, and blurred vision.

Frequently asked questions

What is Hydroxyzine Orifarm used for?+
Hydroxyzine Orifarm is a prescription antihistamine used to treat allergic rhinitis, urticaria (hives), and to provide short‑term relief of anxiety or tension. It is also employed for pre‑operative or post‑operative sedation to help patients relax before or after surgical procedures.
How does hydroxyzine hydrochloride work?+
Hydroxyzine hydrochloride works by selectively blocking peripheral H1 histamine receptors, which reduces the effects of histamine such as itching, swelling, and vasodilation. Its additional anticholinergic and serotonergic activities contribute to its anxiolytic and sedative properties, making it useful for both allergic and calming indications.
What is the usual dose of Hydroxyzine Orifarm?+
The appropriate dose of Hydroxyzine Orifarm is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and response to therapy. Dosage regimens may differ for allergy relief, anxiety management, or procedural sedation, and should always follow the prescriber’s instructions.
Is Hydroxyzine Orifarm safe during pregnancy or breastfeeding?+
Safety data for Hydroxyzine Orifarm in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should only be used when the potential benefit outweighs any possible risk, and the decision should be made in consultation with a qualified healthcare provider.
How do I order Hydroxyzine Orifarm from GNH USA?+
To order Hydroxyzine Orifarm, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.
How does Hydroxyzine Orifarm compare with other antihistamines?+
Hydroxyzine Orifarm belongs to the first‑generation antihistamine class, which typically provides stronger sedation and anxiolytic effects compared with second‑generation agents that are less sedating. While it offers rapid relief of allergic symptoms, its anticholinergic profile may lead to more pronounced side effects such as dry mouth and drowsiness.
How should Hydroxyzine Orifarm be stored and handled?+
Hydroxyzine Orifarm should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and excessive heat. Keep it out of reach of children and do not use it after the expiration date printed on the label.
How is Hydroxyzine Orifarm given or administered?+
Hydroxyzine Orifarm is administered orally, typically as a tablet that is swallowed whole with water. The exact route (e.g., with or without food) and timing depend on the prescriber’s instructions and the therapeutic purpose, such as allergy relief or pre‑operative sedation.
What are the most serious risks to watch for with Hydroxyzine Orifarm?+
Serious risks associated with Hydroxyzine Orifarm include rare but potentially life‑threatening reactions such as anaphylaxis, severe hypotension, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, rapid heartbeat, fainting, or a sudden drop in blood pressure.
Who should not use Hydroxyzine Orifarm?+
Hydroxyzine Orifarm should be avoided in individuals with known hypersensitivity to hydroxyzine or any component of the formulation. Caution is advised for patients with severe cardiac conduction disorders, uncontrolled glaucoma, or those taking other strong CNS depressants. Pregnant or breastfeeding women should only use it under strict medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Hydroxyzine Hydrochloride
Route
Oral Use
Manufacturer
Orifarm Generics A/S
Origin
EU

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