GNH USA

Europe — EMA

Hydroxyzine Orifarm

GNH USA supplies Hydroxyzine Orifarm (Hydroxyzine Hydrochloride), a first‑generation antihistamine for allergic skin conditions, pruritus, anxiety, sedation

Hydroxyzine Hydrochloride

Request sourcing

1
Pack/s

What is Hydroxyzine Hydrochloride?

Hydroxyzine hydrochloride, the active ingredient in Hydroxyzine Orifarm, is a first‑generation antihistamine presented as an oral tablet for oral use. It is employed to alleviate allergic skin conditions, relieve itching, reduce anxiety, provide sedation, and control nausea in adult patients.

GNH USA supplies Hydroxyzine Orifarm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Hydroxyzine Hydrochloride used for?

Hydroxyzine Orifarm is a first‑generation antihistamine that acts on histamine H1 receptors to manage several conditions.

Allergic skin conditions: reduces inflammation and itching associated with urticaria and dermatitis. Pruritus: provides relief from generalized itching not responsive to other therapies. Anxiety: produces a calming effect useful in short‑term management of anxiety. Sedation: induces sleepiness for procedural sedation or insomnia. Nausea: helps control nausea and vomiting related to various causes.

What are the side effects of Hydroxyzine Hydrochloride?

Hydroxyzine may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Drowsiness: feeling unusually sleepy or fatigued. - Dry mouth: reduced salivation leading to a parched sensation. - Dizziness: light‑headedness or unsteady feeling. - Headache: mild to moderate head pain.

Serious or Rare Side Effects: - Cardiac arrhythmia: irregular heart rhythm that may require medical attention. - Severe hypotension: marked drop in blood pressure causing faintness. - Stevens‑Johnson syndrome: rare skin reaction with blistering and detachment.

What precautions apply to Hydroxyzine Hydrochloride?

Before using Hydroxyzine Orifarm, consider the following safety measures.

Elderly patients: increased risk of sedation and falls. Driving or operating machinery: avoid until the effect on alertness is known. Concomitant CNS depressants: may enhance drowsiness and respiratory depression. Pregnancy: safety not established; use only if clearly needed. Renal or hepatic impairment: dose may require adjustment. Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

What does Hydroxyzine Hydrochloride interact with?

Hydroxyzine can interact with other medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid): - CNS depressants: additive sedation and respiratory depression. - Alcohol: enhances drowsiness and impairment. - QT‑prolonging agents: increased risk of cardiac arrhythmias.

Moderate Interactions (Monitor Closely): - CYP3A4 inhibitors: may raise hydroxyzine plasma levels. - Antihypertensives: potential additive blood‑pressure lowering effect.

Frequently asked questions

What is Hydroxyzine Orifarm used for?+
Hydroxyzine Orifarm is a prescription antihistamine indicated for the relief of allergic skin conditions such as urticaria, the control of itching (pruritus), short‑term management of anxiety, procedural sedation, and the treatment of nausea and vomiting associated with various causes.
How does hydroxyzine hydrochloride work?+
Hydroxyzine hydrochloride works by selectively blocking histamine H1 receptors in the body and brain, which prevents histamine‑mediated allergic reactions. Its additional anticholinergic and central sedative actions contribute to its effectiveness in reducing itching, anxiety, and nausea.
What determines the dose of Hydroxyzine Orifarm?+
The appropriate dose of Hydroxyzine Orifarm is determined by the prescribing healthcare professional based on the patient’s age, clinical condition, severity of symptoms, and any relevant medical history. Dosage may be adjusted for renal or hepatic impairment.
Is Hydroxyzine Orifarm safe during pregnancy or breastfeeding?+
Safety of Hydroxyzine Orifarm in pregnancy and lactation has not been conclusively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified prescriber.
How do I order Hydroxyzine Orifarm from GNH USA?+
To order Hydroxyzine Orifarm, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Hydroxyzine compare with other antihistamines?+
Hydroxyzine is a first‑generation antihistamine, distinguished by its pronounced sedative and anticholinergic effects compared with second‑generation agents that cause less drowsiness. It is often chosen when sedation or anxiolysis is desired, whereas newer antihistamines are preferred for daytime allergy relief without significant sedation.
How should Hydroxyzine Orifarm be stored and handled?+
Hydroxyzine Orifarm should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the container tightly closed and out of reach of children.
How is Hydroxyzine Orifarm administered?+
Hydroxyzine Orifarm is administered orally, typically as a tablet that is swallowed whole with water. The exact administration schedule and any special instructions are provided by the prescribing clinician.
What are the most serious risks to watch for with Hydroxyzine Orifarm?+
Serious risks include cardiac arrhythmias, severe hypotension, and rare severe skin reactions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience irregular heartbeat, fainting, or widespread skin blistering.
Who should not use Hydroxyzine Orifarm?+
Hydroxyzine Orifarm should be avoided in individuals with known hypersensitivity to hydroxyzine or other first‑generation antihistamines, in patients with prolonged QT interval, and in those taking other medications that significantly depress the central nervous system unless closely supervised.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Hydroxyzine Hydrochloride
Route
Oral Use
Manufacturer
Orifarm Generics A/S
Origin
EU

Related products