Irbesartan + Hidroclorotiazida Alter Genéricos

Irbesartan and Hydrochlorothiazide, the active ingredients in Irbesartan + Hidroclorotiazida Alter Genéricos, are an Angiotensin II receptor blocker and a thiazide diuretic presented as oral tablets for systemic use. They treat hypertension and associated fluid retention in adult patients and are commonly prescribed in combination therapy.

GNH USA supplies Irbesartan + Hidroclorotiazida Alter Genéricos as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable quality‑assured medication for cardiovascular care across multiple regulatory markets and ensures compliance with EU standards.

Irbesartan/Hydrochlorothiazide is used to manage cardiovascular conditions that involve elevated blood pressure and fluid overload. - Hypertension: lowers systolic and diastolic blood pressure by blocking angiotensin II–mediated vasoconstriction and by increasing urinary sodium and water excretion. - Edema: decreases peripheral fluid accumulation through the diuretic action of hydrochlorothiazide, aiding in the reduction of swelling associated with heart or kidney disease. - Chronic kidney disease with hypertension: helps control systemic blood pressure and may attenuate protein loss in the urine, supporting renal protection in patients with impaired kidney function.

Irbesartan/Hydrochlorothiazide may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Dizziness: feeling of light‑headedness, especially after standing. - Headache: mild to moderate pain in the head region. - Increased urination: more frequent need to void due to diuretic effect.

Serious or Rare Side Effects: - Severe dehydration: excessive fluid loss leading to low blood pressure. - Hyperkalemia: elevated potassium that can affect heart rhythm. - Angioedema: swelling of face, lips, tongue or throat requiring immediate care.

When prescribing Irbesartan/Hydrochlorothiazide, several precautions should be observed to ensure patient safety. - Monitor blood pressure: check regularly to avoid hypotension. - Assess electrolytes: watch for potassium and sodium disturbances. - Evaluate renal function: test creatinine and eGFR before and during therapy. - Avoid use in pregnancy: drug is classified Category D and may harm the fetus. - Use caution in elderly: increased sensitivity to blood pressure changes and dehydration. - Store at room temperature: keep in the original container, protect from moisture and light.

Irbesartan/Hydrochlorothiazide can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid): - Potassium‑sparing diuretics: risk of dangerous hyperkalemia. - ACE inhibitors or aliskiren: additive effects on potassium and renal function. - Lithium: increased lithium levels and toxicity. - NSAIDs: may reduce antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely): - Other antihypertensives: may cause additive hypotension. - Antidiabetic agents: blood glucose may decrease, requiring dose adjustment. - Corticosteroids: can increase sodium retention counteracting diuretic action.