Europe — EMA
Hoggar (Doxylamine Hydrogen Succinate)
Hoggar contains doxylamine hydrogen succinate, an OTC antihistamine and sleep aid in the EU, detailing uses, side effects, precautions, and interactions.
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What is Doxylamine Hydrogen Succinate?
Hoggar is an over‑the‑counter oral medication whose active ingredient is doxylamine hydrogen succinate, a first‑generation antihistamine. It is marketed in the European Union and is supplied in a tablet form for oral use. The product is intended to relieve allergy symptoms and to aid sleep, without requiring a prescription. It contains no controlled substances and follows EU OTC regulations. The formulation is designed for short‑term use.
What is Doxylamine Hydrogen Succinate used for?
Hoggar is commonly used to manage several conditions where histamine release contributes to symptoms. Its antihistamine and sedative properties make it suitable for short‑term relief of the following:
- Relief of occasional insomnia or difficulty falling asleep. - Temporary alleviation of allergic rhinitis symptoms such as sneezing, runny nose, and itchy eyes. - Reduction of nasal congestion and watery discharge associated with the common cold. - Management of mild itching or hives caused by allergic reactions. - Support for nighttime comfort when cold symptoms interfere with sleep.
What are the side effects of Doxylamine Hydrogen Succinate?
Like other first‑generation antihistamines, doxylamine may cause a range of adverse reactions, most of which are mild and transient.
Common: - Drowsiness or feeling of sedation. - Dry mouth, throat, or nasal passages. - Dizziness or light‑headedness. - Blurred vision. - Constipation or difficulty urinating.
Serious: - Severe allergic reaction (rash, itching, swelling, difficulty breathing). - Rapid or irregular heartbeat. - Confusion or hallucinations, especially in older adults. - Persistent vomiting or severe gastrointestinal upset.
What precautions apply to Doxylamine Hydrogen Succinate?
Before using Hoggar, consider the following safety points to minimize risks and ensure appropriate use.
- Avoid use if you have known hypersensitivity to doxylamine or other first‑generation antihistamines. - Do not combine with alcohol, sedatives, or other CNS depressants, as additive drowsiness may occur. - Use caution when driving, operating machinery, or performing tasks requiring alertness. - Pregnant or breastfeeding individuals should consult a healthcare professional before use. - Elderly patients may be more susceptible to sedation and anticholinergic effects; start with the lowest effective dose. - Individuals with glaucoma, enlarged prostate, or urinary retention should discuss use with a clinician.
What does Doxylamine Hydrogen Succinate interact with?
Doxylamine can affect the activity of several other medicines; be aware of the following potential interactions.
Avoid: - Alcohol or other central nervous system depressants (e.g., benzodiazepines, opioids, barbiturates). - Monoamine oxidase inhibitors (MAOIs) or recent MAOI therapy. - Other antihistamines or sleep aids taken concurrently.
Use with caution: - Anticholinergic drugs (e.g., tricyclic antidepressants, antipsychotics) which may increase dry‑mouth or urinary retention. - CNS stimulants (e.g., caffeine, modafinil) that may counteract sedative effects. - Medications metabolized by CYP2D6, as doxylamine may inhibit this pathway.



