Europe — EMA
Hidrocloruro De Fenilefrina Altan 10 Mg/Ml
Learn about Hidrocloruro De Fenilefrina Altan 10 mg/mL, its uses, mechanism, side effects, precautions, and drug interactions for phenylephrine hydrochloride.
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What is Phenylephrine Hydrochloride?
Hidrocloruro De Fenilefrina Altan 10 mg/mL is a phenylephrine hydrochloride solution intended for parenteral administration. The product contains 10 mg of phenylephrine per milliliter and is supplied as an injectable preparation for intramuscular, intravenous, or subcutaneous use. It is marketed in the European Union and requires a prescription.
What is Phenylephrine Hydrochloride used for?
Hidrocloruro De Fenilefrina Altan is employed in clinical settings where rapid vasoconstriction is needed. It is commonly used for: - Treatment of acute hypotension, especially during anesthesia or shock. - Relief of nasal congestion caused by allergic or viral rhinitis. - Management of upper airway edema, such as after intubation or surgery. - Adjunct therapy for certain types of bronchial obstruction. - Supportive care in patients with severe allergic reactions where airway swelling is present.
What are the side effects of Phenylephrine Hydrochloride?
Adverse reactions to phenylephrine may vary in frequency and severity.
Common: - Headache - Palpitations or tachycardia - Hypertension or transient blood pressure elevation - Nausea or vomiting - Local irritation at the injection site
Serious: - Severe hypertension with risk of end‑organ damage - Cardiac arrhythmias, including atrial fibrillation - Reflex bradycardia - Ischemic chest pain or myocardial infarction - Cerebral hemorrhage in susceptible individuals
What precautions apply to Phenylephrine Hydrochloride?
Use of phenylephrine requires careful assessment of patient risk factors. Consider the following precautions: - Assess baseline blood pressure; avoid use in uncontrolled hypertension. - Monitor cardiac rhythm in patients with known arrhythmias. - Use cautiously in patients with coronary artery disease or recent myocardial infarction. - Evaluate for hyperthyroidism, as increased catecholamine sensitivity may amplify effects. - Adjust dose or avoid in patients receiving monoamine oxidase inhibitors (MAOIs). - Pregnant or nursing patients should be managed only if benefits outweigh potential risks.
What does Phenylephrine Hydrochloride interact with?
Phenylephrine can interact with several medication classes. Relevant interactions include:
Avoid: - Concurrent use with other potent vasoconstrictors (e.g., norepinephrine, epinephrine) due to additive hypertension risk. - MAO inhibitors, which may potentiate hypertensive responses. - Tricyclic antidepressants that increase norepinephrine levels.
Use with caution: - Beta‑blockers, which may mask tachycardia while allowing blood pressure rise. - Diuretics or antihypertensives, as phenylephrine may counteract their effects. - Lithium, because altered renal perfusion can affect lithium clearance.
Frequently asked questions
What is the primary therapeutic class of Hidrocloruro De Fenilefrina Altan?+
Which routes of administration are approved for this phenylephrine product?+
Can Hidrocloruro De Fenilefrina Altan be used to treat nasal congestion?+
Is phenylephrine hydrochloride available over the counter?+
What should be monitored when administering phenylephrine to a patient with hypertension?+
How does phenylephrine differ from epinephrine in its mechanism?+
Are there any specific contraindications for this medication?+
What are common adverse reactions after an intramuscular injection of phenylephrine?+
Should phenylephrine be used in pregnant women?+
Can phenylephrine interact with beta‑blocker therapy?+
What is the typical concentration of phenylephrine in this product?+
Is there a risk of reflex bradycardia with phenylephrine use?+
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