Hexarhinal Plus

Hexarhinal Plus is an over‑the‑counter nasal spray that combines xylometazoline hydrochloride with dexpanthenol. The product is formulated for topical nasal administration; exact strength and dosage form are not disclosed in the public label, but it is marketed in the European Union as a nasal decongestant and mucosal protectant. It is intended for temporary relief of nasal blockage and to help maintain moisture of the nasal passages.

Hexarhinal Plus is indicated for symptomatic relief of nasal congestion and dryness associated with common colds, sinusitis, or allergic rhinitis.

- Temporary relief of nasal blockage caused by upper‑respiratory infections. - Reduction of swelling of the nasal mucosa due to allergic reactions. - Moisturizing of irritated nasal passages. - Support of mucosal healing when dryness is present. - Adjunctive use during the early phase of a cold to improve breathing comfort.

Adverse reactions to Hexarhinal Plus are generally mild and reversible, but rare serious events have been reported.

Common: - Transient nasal burning or stinging sensation. - Mild nasal dryness or irritation. - Sneezing shortly after application. - Temporary headache. - Nasal itching. - Dry throat.

Serious: - Persistent nasal bleeding (epistaxis). - Severe allergic reaction such as rash, itching, swelling, or difficulty breathing. - Nasal septum perforation with prolonged use. - Elevated blood pressure in susceptible individuals. - Vision changes. - Rapid heart rate (tachycardia).

Before using Hexarhinal Plus, consider the following precautions to minimize risks and ensure appropriate use.

- Limit use to no more than three consecutive days to avoid rebound congestion. - Avoid in patients with known hypersensitivity to xylometazoline, dexpanthenol, or any formulation components. - Use cautiously in individuals with hypertension, heart disease, diabetes, or thyroid disorders. - Do not use in children under the age specified by local regulations without medical advice. - Pregnant or breastfeeding women should consult a healthcare professional before use. - If symptoms persist or worsen, discontinue and seek medical evaluation.

Hexarhinal Plus may interact with certain systemic medications or other nasal products; consider the following guidance.

Avoid: - Concurrent use of other topical nasal decongestants (e.g., oxymetazoline, phenylephrine) to prevent additive vasoconstriction. - Monoamine oxidase inhibitors (MAOIs) when used systemically, due to potential hypertensive response.

Use with caution: - Systemic sympathomimetic agents such as pseudoephedrine or ephedrine. - Antihypertensive drugs, especially beta‑blockers or ACE inhibitors. - Nasal corticosteroid sprays, which may increase local irritation. - Herbal decongestants or supplements containing ephedra.