Europe — EMA
Hexaflu Day & Night
Learn about Hexaflu Day & Night, an OTC oral combo of diphenhydramine, pseudoephedrine and paracetamol for allergy, cold, flu and pain relief.
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What is Diphenhydramine Hydrochloride, Paracetamol | Pseudoephedrine Hydrochloride, Paracetamol?
Hexaflu Day & Night is an over‑the‑counter oral medication that combines diphenhydramine hydrochloride with paracetamol in one formulation and pseudoephedrine hydrochloride with paracetamol in another. Marketed in the European Union, it is supplied as tablets (strength not specified) for mouth administration. The product provides antihistamine, analgesic and decongestant actions to relieve allergy, cold, flu and pain symptoms. It is intended for short‑term use and does not require a prescription.
What is Diphenhydramine Hydrochloride, Paracetamol | Pseudoephedrine Hydrochloride, Paracetamol used for?
Hexaflu Day & Night is indicated for the temporary relief of several common upper‑respiratory and pain conditions.
- Relief of allergic rhinitis symptoms such as sneezing, itching and watery eyes. - Reduction of nasal congestion associated with the common cold or sinusitis. - Alleviation of mild to moderate headache or body aches. - Lowering of fever caused by viral infections. - Management of minor pain from sore throat or muscle strain. - Support for relief of sinus pressure and facial pain. - Temporary easing of ear congestion during upper‑respiratory infections.
What are the side effects of Diphenhydramine Hydrochloride, Paracetamol | Pseudoephedrine Hydrochloride, Paracetamol?
Like all medicines, Hexaflu Day & Night may cause unwanted effects, most of which are mild, transient, and resolve without medical intervention.
Common: - Drowsiness or mild sedation, particularly after the diphenhydramine component. - Dry mouth, throat irritation, or occasional blurred vision. - Nausea, stomach discomfort, or reduced appetite. - Slight headache or a feeling of restlessness. - Mild insomnia or difficulty sleeping if taken later in the day.
Serious: - Allergic skin reaction such as rash, itching, swelling, or hives. - Rapid heartbeat, palpitations, or significant increase in blood pressure. - Difficulty breathing, tight chest, or severe dizziness that may indicate a serious reaction. - Unusual mental changes such as confusion, agitation, or hallucinations.
What precautions apply to Diphenhydramine Hydrochloride, Paracetamol | Pseudoephedrine Hydrochloride, Paracetamol?
Before using Hexaflu Day & Night, consider the following precautions to ensure safe and appropriate use.
- Do not exceed the recommended daily dose of each active ingredient. - Avoid use in children under the age specified on the packaging without medical advice. - Use caution if you have high blood pressure, heart disease, glaucoma, or thyroid disorders. - Pregnant or breastfeeding individuals should consult a healthcare professional before taking the product. - Alcohol or other sedating medications may increase drowsiness. - If symptoms persist longer than a few days, seek medical evaluation.
What does Diphenhydramine Hydrochloride, Paracetamol | Pseudoephedrine Hydrochloride, Paracetamol interact with?
Hexaflu Day & Night can interact with other medicines; be aware of the following potential interactions.
Avoid: - Monoamine oxidase inhibitors (MAOIs) or other sympathomimetic drugs, which may cause excessive cardiovascular stimulation. - Other antihistamines or sedatives, which can increase drowsiness. - Additional paracetamol‑containing products, to avoid exceeding the safe daily limit. - Certain decongestant nasal sprays, which may cause additive vasoconstriction.
Use with caution: - Blood pressure medications, as pseudoephedrine may reduce their effectiveness. - Antidepressants such as SSRIs or tricyclics, which may increase the risk of serotonin syndrome. - Alcohol, which can enhance sedation from diphenhydramine. - Anticoagulants or antiplatelet agents, because paracetamol may increase bleeding risk.
Frequently asked questions
What active ingredients are combined in Hexaflu Day & Night?+
Is Hexaflu Day & Night available without a prescription in the EU?+
Can I take Hexaflu Day & Night if I have high blood pressure?+
What symptoms is Hexaflu Day & Night designed to relieve?+
Should I avoid alcohol while taking Hexaflu Day & Night?+
How does diphenhydramine work in this product?+
What is the role of paracetamol in Hexaflu Day & Night?+
Can I use Hexaflu Day & Night together with other cold medicines?+
Is Hexaflu Day & Night safe for children?+
What should I do if I experience a rash after taking Hexaflu Day & Night?+
Does Hexaflu Day & Night cause drowsiness?+
Can Hexaflu Day & Night be used during pregnancy?+
Product details
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