Europe — EMA
Hexaflu Day & Night
Hexaflu Day & Night is an OTC oral combo of diphenhydramine, paracetamol and pseudoephedrine for cold, flu and allergy symptom relief.
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What is Diphenhydramine Hydrochloride, Paracetamol | Pseudoephedrine Hydrochloride, Paracetamol?
Hexaflu Day & Night is an over‑the‑counter oral medication that combines diphenhydramine hydrochloride, paracetamol, and pseudoephedrine hydrochloride. It is formulated to provide multi‑symptom relief for cold and flu, including allergy, pain, fever, and nasal congestion. The product is marketed in the European Union and is supplied as an oral tablet. Each tablet combines an antihistamine, an analgesic/antipyretic and a nasal decongestant for convenient day‑and‑night symptom control.
What is Diphenhydramine Hydrochloride, Paracetamol | Pseudoephedrine Hydrochloride, Paracetamol used for?
Hexaflu Day & Night is indicated for temporary relief of several common cold, flu and allergy symptoms.
- Relief of nasal congestion and sinus pressure associated with colds or allergic rhinitis. - Reduction of headache, muscle aches, and fever through analgesic and antipyretic action. - Alleviation of sneezing, itchy eyes, and runny nose caused by histamine release. - Support for daytime symptom control when decongestion is needed without excessive sedation. - Nighttime use to manage allergy‑related insomnia and discomfort while maintaining pain relief.
What are the side effects of Diphenhydramine Hydrochloride, Paracetamol | Pseudoephedrine Hydrochloride, Paracetamol?
Like many combination cold medicines, Hexaflu Day & Night may cause a range of adverse reactions, most of which are mild and transient.
Common: - Drowsiness or mild sedation, especially from diphenhydramine. - Dry mouth, throat or nasal passages. - Nausea, stomach discomfort or loss of appetite. - Light‑headedness or mild dizziness.
Serious: - Rapid heart rate, palpitations, or high blood pressure. - Severe allergic reactions such as rash, itching, swelling, or difficulty breathing. - Hallucinations or confusion, particularly in older adults. - Persistent vomiting or signs of liver stress.
What precautions apply to Diphenhydramine Hydrochloride, Paracetamol | Pseudoephedrine Hydrochloride, Paracetamol?
Before using Hexaflu Day & Night, consider the following precautions to ensure safe and appropriate use.
- Avoid use if you have known hypersensitivity to any component. - Use caution in patients with hypertension, heart disease, diabetes, or thyroid disorders. - Not recommended for children under a specified age without medical advice. - Limit use if you are taking other products containing paracetamol or decongestants to prevent overdose. - Pregnant or breastfeeding individuals should consult a healthcare professional before use. - Alcohol consumption may increase drowsiness and liver strain.
What does Diphenhydramine Hydrochloride, Paracetamol | Pseudoephedrine Hydrochloride, Paracetamol interact with?
Hexaflu Day & Night can interact with several medicines; reviewing these interactions helps prevent adverse effects.
Avoid: - Other antihistamines, sedatives, or CNS depressants that may enhance drowsiness. - Additional decongestants or sympathomimetic agents that could raise blood pressure. - Monoamine‑oxidase inhibitors (MAOIs) or recent MAOI therapy.
Use with caution: - Anticoagulants or antiplatelet drugs, due to potential increased bleeding risk with paracetamol. - Certain antidepressants (e.g., SSRIs) that may affect serotonin levels. - Medications metabolized by CYP2D6, as diphenhydramine can inhibit this pathway.
Frequently asked questions
What symptoms does Hexaflu Day & Night treat?+
Can I take Hexaflu Day & Night if I have high blood pressure?+
Is Hexaflu Day & Night safe for pregnant women?+
How does diphenhydramine in Hexaflu Day & Night work?+
What is the role of paracetamol in this combination?+
Why is pseudoephedrine included in Hexaflu Day & Night?+
Can I take other cold medicines with Hexaflu Day & Night?+
What should I do if I experience severe dizziness after taking Hexaflu Day & Night?+
Is alcohol consumption allowed while using Hexaflu Day & Night?+
How often can I take Hexaflu Day & Night?+
Can children use Hexaflu Day & Night?+
What are signs of an allergic reaction to Hexaflu Day & Night?+
Product details
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