GNH USA

Europe — EMA

Hemosol B0

GNH USA supplies Hemosol B0 (Electrolyte solution), a dialysis fluid for haemodialysis and intravenous fluid replacement.

Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate

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What is Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate?

Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate, the active ingredient in Hemosol B0, is an electrolyte solution presented as a solution for injection for haemodialysis and intravenous use. It corrects electrolyte and acid‑base imbalances during haemodialysis and provides fluid replacement in patients requiring intravenous therapy.

GNH USA supplies Hemosol B0 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and dialysis clinics worldwide.

What is Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate used for?

Hemosol B0, an electrolyte solution used in renal replacement therapy, is indicated for: - Hemodialysis: restores electrolyte balance and corrects acid‑base disturbances during treatment. - Intravenous fluid replacement: provides essential electrolytes and volume support in patients with fluid loss. - Electrolyte balance correction: corrects deficiencies of calcium, magnesium, sodium, chloride and bicarbonate in various clinical settings.

What are the side effects of Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate?

Common Side Effects: - Mild hypercalcemia: transient elevation of serum calcium. - Transient hypotension: slight drop in blood pressure during infusion. - Local irritation at infusion site: redness or discomfort. - Nausea: occasional feeling of queasiness. - Headache: mild to moderate.

Serious or Rare Side Effects: - Severe hypermagnesemia: high magnesium levels causing cardiac effects. - Metabolic alkalosis: excessive bicarbonate leading to elevated pH. - Anaphylactic reaction: rare severe allergic response. - Electrolyte overload: risk of arrhythmia due to excess ions.

What precautions apply to Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate?

Before initiating therapy, evaluate the patient’s baseline electrolyte and acid‑base status. - Assess electrolyte levels: check serum calcium, magnesium, sodium and bicarbonate. - Monitor during infusion: frequent laboratory checks to avoid overload. - Adjust rate in cardiac disease: slower infusion for patients with heart failure. - Use caution in renal impairment: reduced clearance may increase risk. - Store at ambient temperature: keep in original container, protect from light and moisture.

What does Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate interact with?

Major Interactions (Avoid): - Calcium‑containing antacids: may cause hypercalcemia. - Magnesium sulfate infusion: risk of hypermagnesemia. - Sodium bicarbonate infusion: may lead to electrolyte overload.

Moderate Interactions (Monitor Closely): - Loop diuretics: can alter electrolyte balance. - ACE inhibitors: may affect potassium and overall electrolyte status. - Blood transfusions: can influence calcium levels.

Frequently asked questions

What is Hemosol B0 used for?+
Hemosol B0 is an electrolyte solution used primarily during haemodialysis and as an intravenous fluid replacement. It helps correct electrolyte imbalances, supports acid‑base regulation, and provides necessary ions such as calcium, magnesium, sodium, chloride and bicarbonate to patients undergoing renal replacement therapy or those needing rapid fluid and electrolyte repletion.
How does the active ingredient work?+
The solution delivers calcium, magnesium, sodium, chloride, bicarbonate and lactic acid directly into the bloodstream or dialysis circuit. These ions dissolve and integrate into the extracellular fluid, restoring normal electrolyte concentrations and buffering capacity. Bicarbonate and lactate act as pH buffers, while calcium and magnesium support cardiac and neuromuscular function, collectively correcting the disturbances seen in dialysis or fluid loss.
What is the usual dose?+
Dosing of Hemosol B0 is individualized. The prescribing clinician determines the volume and rate based on the patient’s current electrolyte profile, fluid status, and the specific requirements of the dialysis session or intravenous therapy. No fixed regimen is provided; dosage is adjusted to achieve target laboratory values and clinical goals.
Is it safe in pregnancy or breastfeeding?+
Safety data for Hemosol B0 in pregnancy and lactation are limited. Because it contains essential electrolytes, it may be used when the potential benefit outweighs any theoretical risk, but the decision must be made by the treating physician after careful consideration of maternal and fetal health.
How do I order Hemosol B0 from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does it compare with the main alternative dialysis fluids?+
Compared with standard bicarbonate‑based dialysis fluids, Hemosol B0 adds calcium, magnesium and lactate, offering a more comprehensive electrolyte profile. This can reduce the need for supplemental infusions during treatment. However, the choice depends on the patient’s individual electrolyte needs, the dialysis protocol and institutional preferences.
What are the storage and handling requirements?+
Hemosol B0 should be stored at ambient temperature, preferably below 25 °C. Keep the container sealed, protect it from direct sunlight, moisture and extreme temperature fluctuations. Do not freeze the solution, and inspect the vial for any particulate matter before use.
How is it given or administered?+
The solution is administered either as part of the haemodialysis circuit, where it mixes with the dialysate, or as an intravenous infusion through a calibrated infusion set. Administration rate is set by the clinician according to the patient’s electrolyte targets and overall fluid balance.
What are the most serious risks to watch for?+
Serious risks include severe hypermagnesemia, metabolic alkalosis, anaphylactic reactions and electrolyte overload that can precipitate cardiac arrhythmias. Continuous monitoring of serum electrolytes and acid‑base status during therapy helps detect these complications early.
Who should not use Hemosol B0?+
Patients with known hypersensitivity to any component of the solution should avoid it. Caution is also advised for individuals with uncontrolled cardiac disease, severe renal impairment not on dialysis, or those already receiving high‑dose electrolyte supplements that could lead to overload.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate
Route
Haemodialysis , Intravenous Use
Manufacturer
Vantive Belgium
Origin
EU

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