Hemorapyd (Cinchocaine Hydrochloride, Policresulen)

Hemorapyd, containing the active ingredients cinchocaine hydrochloride and policresulen, is a rectally administered preparation (strength not specified) marketed in the European Union. It combines a local anesthetic with a hemostatic and antiseptic agent to provide symptomatic relief and promote tissue healing in the anorectal area. The product is intended for use under medical supervision for conditions affecting the rectum and anal canal.

Hemorapyd is indicated for the symptomatic management of several anorectal conditions where local anesthesia and hemostasis are beneficial.

- Relief of pain and discomfort associated with hemorrhoids. - Treatment of minor anal fissures to reduce spasm and bleeding. - Management of rectal bleeding of non‑infectious origin. - Adjunctive care after minor anorectal procedures. - Support of tissue regeneration in mild rectal irritation.

Side effects of Hemorapyd are generally mild and related to its local action, but rare serious reactions may occur.

Common: - Mild burning or stinging at the application site. - Transient numbness or tingling in the rectal area. - Itching or mild irritation. - Temporary redness or mild swelling. - Slight discomfort during application.

Serious: - Allergic reaction such as rash, swelling, or hives. - Severe burning or ulceration of the mucosa. - Persistent numbness lasting beyond 24 hours. - Signs of systemic toxicity (e.g., dizziness, tinnitus). - Severe local infection.

When using Hemorapyd, consider the following precautions to minimize risks and ensure appropriate use.

- Do not apply to broken skin, open wounds, or infected areas without medical advice. - Avoid use in patients with known hypersensitivity to cinchocaine, policresulen, or related compounds. - Use cautiously in individuals taking anticoagulant or antiplatelet therapy due to potential increased bleeding. - Pregnant or breastfeeding women should consult a healthcare professional before use. - Keep the product out of reach of children and store at room temperature away from moisture. - Discontinue use and seek medical attention if severe irritation or allergic symptoms develop.

Hemorapyd may interact with other medications or substances applied to the same area or absorbed systemically.

Avoid: - Concurrent use of other topical anesthetics containing lidocaine or similar agents, which may increase systemic exposure. - Application together with potent vasoconstrictors that could impair local blood flow.

Use with caution: - Anticoagulants or antiplatelet drugs, as they may affect bleeding control. - Systemic medications that lower seizure threshold, given the potential for local anesthetic absorption. - Herbal or over‑the‑counter rectal preparations, which could alter mucosal integrity.