Europe — EMA
Haselnuss Hal Allergy (Hazelnut)
Learn about Haselnuss Hal Allergy, a hazelnut extract diagnostic allergen for skin testing to identify hazelnut allergy in the EU.
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What is Hazelnut?
Haselnuss Hal Allergy is a diagnostic allergen product containing hazelnut extract, supplied in a cutaneous testing format. It is intended for use in the European market to support the identification of IgE-mediated hypersensitivity to hazelnut. The preparation is applied to the skin during allergy testing and is not a therapeutic medication. The product is packaged in a sealed vial for application and complies with EU regulatory standards for diagnostic allergens.
What is Hazelnut used for?
Haselnuss Hal Allergy is employed primarily as a diagnostic tool to assess sensitization to hazelnut in patients suspected of having a food allergy.
- Skin prick testing to detect immediate‑type hypersensitivity to hazelnut. - Confirmation of hazelnut allergy when clinical history is unclear. - Differentiation of hazelnut allergy from other tree‑nut sensitivities. - Guidance for dietary management and avoidance strategies. - Support for clinicians in allergy clinics and specialist centers.
What are the side effects of Hazelnut?
Skin testing with hazelnut extract may cause local reactions; most are mild and transient, while rare systemic responses can occur.
Common: - Redness at the test site. - Small swelling or wheal formation. - Itching or mild discomfort. - Minor hives limited to the area of application.
Serious: - Large wheal or flare extending beyond the test site. - Systemic urticaria. - Respiratory symptoms such as wheezing or shortness of breath. - Anaphylaxis (rare but requires immediate medical attention).
What precautions apply to Hazelnut?
When using Haselnuss Hal Allergy, clinicians should observe several safety measures to minimize risk.
- Verify that the patient has no history of severe anaphylaxis to hazelnut before testing. - Avoid testing on broken, inflamed, or infected skin. - Ensure emergency equipment (e.g., epinephrine) is readily available. - Use the product under the supervision of trained healthcare personnel. - Consider age‑related guidelines; pediatric testing may require adjusted protocols. - Document any prior antihistamine or medication use that could affect results.
What does Hazelnut interact with?
Certain medications and conditions can influence the outcome of hazelnut skin testing or increase risk.
Avoid: - Antihistamines or other mast cell stabilizers taken within 48–72 hours, as they may suppress skin reactivity. - Recent systemic corticosteroids that could diminish test responses.
Use with caution: - Beta‑blockers, which may interfere with treatment of severe reactions. - Ongoing allergen immunotherapy, which could alter skin test sensitivity. - ACE inhibitors, due to potential enhancement of angioedema. - Patients with uncontrolled asthma, requiring careful monitoring during testing.


