Europe — EMA
Haliver (Thiocolchicoside)
Haliver is a EU‑marketed topical product containing thiocolchicoside, used for muscle tension relief and skin discomfort. Learn its uses, effects, and safety.
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What is Thiocolchicoside?
Haliver is a cutaneous medication that contains the active ingredient thiocolchicoside. Marketed in the European Union, the product’s specific strength and dosage form are not publicly disclosed, but it is intended for topical application. Thiocolchicoside belongs to a class of muscle relaxants used in various formulations. Haliver is supplied without a defined prescription status, and its labeling follows EU regulatory standards and complies with current EU regulatory standards.
What is Thiocolchicoside used for?
Haliver is generally considered for conditions where muscle tension or spasm of the skin and underlying tissues may contribute to discomfort.
- Relief of mild to moderate muscle tension in superficial soft tissues. - Adjunctive support for localized musculoskeletal discomfort. - Management of minor skin-associated stiffness following minor injuries. - Use as part of a multimodal approach for tension‑related skin irritation.
What are the side effects of Thiocolchicoside?
Topical application of thiocolchicoside may be associated with a range of local and systemic effects, most of which are mild and reversible.
Common: - Transient skin redness at the application site. - Mild itching or tingling sensation. - Temporary warmth or cooling feeling. - Slight swelling that resolves within hours.
Serious: - Allergic dermatitis with blistering or rash. - Persistent ulceration or necrosis of the skin. - Systemic muscle weakness if absorbed in large amounts.
What precautions apply to Thiocolchicoside?
When considering Haliver, several precautionary measures should be reviewed to minimize risk and ensure appropriate use.
- Avoid application on broken, infected, or inflamed skin. - Do not use on extensive body areas without medical guidance. - Discontinue if signs of allergic reaction develop. - Keep out of reach of children and pets. - Store at room temperature, protected from moisture and direct sunlight. - Consult a healthcare professional before use during pregnancy or lactation, despite limited data.
What does Thiocolchicoside interact with?
Thiocolchicoside can interact with other topical agents or systemic medications, influencing its safety profile.
Avoid: - Concurrent use with other muscle‑relaxant creams or gels containing similar active ingredients. - Application together with potent corticosteroid ointments on the same area. - Use alongside photosensitizing agents before exposure to strong UV light.
Use with caution: - Combining with systemic muscle relaxants may increase overall muscle‑relaxant effect. - Co‑application with topical anesthetics should be monitored for enhanced skin absorption. - Use with caution in patients taking anticoagulants due to potential bruising risk.



