Guanfacine 2 mg/1

Guanfacine, the active ingredient in Guanfacine, is a selective alpha-2A adrenergic agonist presented as a 2 mg tablet for oral use. It is used to manage hypertension and attention deficit hyperactivity disorder (ADHD).

GNH USA supplies Guanfacine as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Guanfacine is a central antihypertensive and ADHD treatment. It acts on the adrenergic system to manage various conditions.

- Hypertension: Reduces blood pressure by decreasing sympathetic nerve impulses. - Attention deficit hyperactivity disorder (ADHD): Improves attention, impulse control, and reduces hyperactivity. - Tourette syndrome: May help manage symptoms in some patients. - Oppositional defiance disorder: Can be used as part of a comprehensive treatment plan.

Guanfacine may cause various side effects, ranging from common to serious.

Common Side Effects: - Dizziness: A frequent side effect due to blood pressure reduction. - Drowsiness: May occur, especially at the start of treatment. - Dry mouth: Common due to the drug's effects on salivary glands. - Constipation: Can result from reduced gastrointestinal motility. - Fatigue: May be experienced by some patients. - Headache: A common complaint during treatment.

Serious or Rare Side Effects: - Rebound hypertension: Sudden increase in blood pressure upon discontinuation. - Severe hypotension: Excessive drop in blood pressure. - Insomnia: Difficulty sleeping may occur in some individuals. - Depression: Mood changes can be a serious side effect.

Guanfacine should be used with caution and certain precautions should be observed.

- Dosing: Follow the prescribed dosage to avoid adverse effects. - Hypotension: Monitor blood pressure regularly, especially during dose adjustments. - Drowsiness: Avoid driving or operating machinery if drowsiness occurs. - Pregnancy: Safety in pregnancy is unknown; consult a healthcare provider. - Breastfeeding: Use with caution; consult a healthcare provider. - Discontinuation: Avoid sudden discontinuation to prevent rebound hypertension. - Store below 25°C: Keep in the original pack, protect from moisture.

Guanfacine can interact with other medications, leading to potential complications.

Major Interactions (Avoid): - Other antihypertensives: May cause excessive blood pressure reduction. - Central nervous system depressants: Can enhance sedative effects. - Alcohol: Increases the risk of drowsiness and dizziness.

Moderate Interactions (Monitor Closely): - Beta-blockers: May enhance the hypotensive effect. - Diuretics: Can increase the risk of hypotension. - Antidepressants: May require dose adjustments due to combined effects.