Europe — EMA
Glycerine Suppo’s Volwassenen Kela (Glycerol)
Glycerine Suppo’s Volwassenen Kela glycerol suppository provides OTC relief for adult constipation with a gentle osmotic action.
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What is Glycerol?
Glycerine Suppo’s Volwassenen Kela is an over‑the‑counter rectal suppository that contains glycerol as the sole active ingredient. It is formulated as a single‑strength, solvent‑based laxative designed for adult use in the European market. The product works by drawing water into the rectum to soften stool and promote natural evacuation, providing a non‑systemic option for occasional constipation relief.
What is Glycerol used for?
Glycerine Suppo’s Volwassenen Kela is indicated for the temporary relief of constipation in adults. It may also be used in preparation for certain medical examinations that require an empty rectum.
- Relief of occasional constipation when dietary measures are insufficient. - Softening of hard stool to facilitate natural bowel movements. - Preparation for rectal examinations or procedures that require a clear rectum. - Use as a short‑term osmotic laxative under the guidance of a healthcare professional. - Suitable for adults who prefer a rectal route over oral laxatives.
What are the side effects of Glycerol?
Side effects of glycerol suppositories are generally mild and related to local irritation. Serious adverse events are rare but should be recognized promptly.
Common: - Mild rectal burning or stinging sensation. - Minor irritation or redness at the insertion site. - Slight cramping or abdominal discomfort. - Loose stools or mild diarrhea following use.
Serious: - Persistent rectal bleeding. - Severe abdominal pain or bloating. - Signs of allergic reaction such as rash, itching, or swelling. - Unexpected electrolyte imbalance with prolonged overuse.
What precautions apply to Glycerol?
Before using Glycerine Suppo’s Volwassenen Kela, consider the following precautions to ensure safe and effective use.
- Do not use if you have a known allergy to glycerol or any excipients. - Avoid prolonged or excessive use, as it may lead to electrolyte disturbances. - Consult a healthcare professional if constipation persists for more than a few days. - Use with caution in patients with inflammatory bowel disease, rectal bleeding, or recent rectal surgery. - Keep out of reach of children; accidental insertion can cause irritation. - Do not use in pregnancy or breastfeeding without medical advice, as safety data are limited.
What does Glycerol interact with?
Glycerine Suppo’s Volwassenen Kela has a low potential for systemic drug interactions, but certain situations warrant attention.
Avoid: - Concurrent use of other strong osmotic or stimulant laxatives, which may increase the risk of dehydration. - Insertion of the suppository immediately after rectal administration of medications that could be washed out.
Use with caution: - Anticholinergic agents that may reduce bowel motility. - Diuretic therapy, as combined fluid loss could affect electrolyte balance. - Medications that cause constipation as a side effect (e.g., opioids, calcium channel blockers). - Any systemic therapy that requires stable electrolyte levels.



