Europe — EMA
Glycerine Suppo’s Adultes Kela (Glycerol)
Learn about Glycerine Suppo’s Adultes Kela glycerol suppository—uses, side effects, precautions, and FAQs for adult constipation relief.
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What is Glycerol?
Glycerine Suppo’s Adultes Kela is an over‑the‑counter glycerol (glycerine) suppository marketed in the European Union. Each rectal suppository contains glycerol as the active ingredient, formulated to act as an osmotic laxative. The product is intended for adult use and is supplied without a specified strength label. It works by drawing water into the colon to soften stool and promote a bowel movement in a safe and predictable manner.
What is Glycerol used for?
Glycerine Suppo’s Adultes Kela is indicated for the temporary relief of constipation in adults.
- Relief of occasional constipation due to hard or dry stool. - Preparation for diagnostic procedures that require bowel emptying. - Adjunct therapy for patients with reduced intestinal motility. - Short‑term use after surgery or medication that slows gut transit. - Management of constipation associated with limited physical activity. - Support for bowel regularity during periods of reduced activity.
What are the side effects of Glycerol?
The most frequently reported effects of glycerol suppositories are related to local irritation and changes in bowel habits. These effects are usually mild and resolve after discontinuation of the product.
Common: - Mild rectal burning or stinging sensation. - Softening of stool leading to loose stools. - Increased frequency of bowel movements. - Minor abdominal cramping. - Feeling of urgency to defecate. - Transient rectal discharge of watery fluid.
Serious: - Severe rectal pain or ulceration. - Persistent diarrhea causing dehydration. - Signs of allergic reaction such as rash, itching, or swelling. - Rectal bleeding. - Signs of electrolyte imbalance such as muscle weakness or irregular heartbeat.
What precautions apply to Glycerol?
When using Glycerine Suppo’s Adultes Kela, certain precautions should be observed to minimize risk and ensure appropriate use.
- Do not use for chronic constipation without medical advice. - Avoid use in individuals with known hypersensitivity to glycerol. - Limit use to adults; safety in children and adolescents has not been established. - Do not insert more than one suppository at a time. - Discontinue if severe rectal pain, bleeding, or persistent diarrhea occurs. - Consult a healthcare professional if pregnant or breastfeeding. - Store at room temperature away from moisture.
What does Glycerol interact with?
Glycerol suppositories have limited systemic absorption, but they may interact with certain medications or conditions.
Avoid: - Concurrent use with other osmotic or stimulant laxatives, which may increase the risk of electrolyte imbalance. - Use in patients with intestinal obstruction or perforation.
Use with caution: - Medications that can cause diarrhea, such as certain antibiotics or magnesium‑containing antacids. - Diuretics, as fluid loss from diarrhea may potentiate dehydration. - Electrolyte‑altering drugs (e.g., ACE inhibitors, potassium‑sparing diuretics). - Patients with renal impairment, where fluid shifts require monitoring.



