Europe — EMA
Glycerine Volwassenen Lambo (Glycerol)
Learn about Glycerine Volwassenen Lambo glycerol rectal lubricant, its uses, side effects, precautions, and interactions – an OTC EU excipient.
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What is Glycerol?
Glycerine Volwassenen Lambo is an over‑the‑counter rectal preparation whose sole active ingredient is glycerol. The product is supplied without a specified strength or dosage form, and it is marketed within the European Union as an excipient used for moisture and lubrication. As a solvent and lubricant, it is intended to facilitate the administration of rectal drug formulations and to provide local lubrication during clinical procedures.
What is Glycerol used for?
Designed for rectal application, Glycerine Volwassenen Lambo supplies moisture and lubrication, helping to ease the insertion of suppositories, enemas, and other rectally administered medications while supporting patient comfort. - Facilitates insertion of rectal suppositories by reducing friction. - Acts as a solvent for rectal drug preparations, enhancing dispersion. - Provides temporary lubrication for enemas and cleansing procedures. - Supports mucosal hydration, potentially improving patient tolerance. - May be used to dilute highly concentrated rectal formulations under professional guidance. - Serves as a carrier for combination rectal products containing active pharmaceuticals.
What are the side effects of Glycerol?
When applied rectally, the glycerol component of Glycerine Volwassenen Lambo can cause local reactions that are usually mild and self‑limiting, while infrequent but more serious events have been reported in isolated cases.
Common: - Mild irritation or redness at the application site. - Transient watery discharge or increased stool softness. - Slight burning sensation that resolves within minutes. - Temporary increase in gas or flatulence. - Mild itching or pruritus around the anal area.
Serious: - Persistent ulceration or erosion of rectal mucosa. - Severe allergic reaction presenting as swelling, rash, or difficulty breathing. - Unexplained rectal bleeding requiring medical evaluation. - Development of fistula or chronic inflammation (very rare). - Systemic absorption leading to electrolyte imbalance (extremely rare).
What precautions apply to Glycerol?
Glycerine Volwassenen Lambo should be used with attention to specific safety considerations to minimize irritation and ensure appropriate application. - Use only the amount recommended by a healthcare professional; excess may increase irritation. - Avoid application if the rectal mucosa is visibly damaged, inflamed, or infected. - Do not combine with other rectal lubricants unless advised, as mixtures can alter osmolarity. - Keep the product out of reach of children; accidental ingestion can cause gastrointestinal upset. - Store in a cool, dry place away from direct sunlight to preserve stability. - Discontinue use and seek medical advice if persistent discomfort or bleeding occurs. - Do not use during pregnancy or lactation without professional guidance (safety not established).
What does Glycerol interact with?
Glycerine Volwassenen Lambo may interact with other rectally administered agents, influencing absorption or causing additive irritation.
Avoid: - Avoid simultaneous use with strong irritant enemas (e.g., sodium phosphate) that could exacerbate mucosal damage. - Do not mix with alcohol‑based rectal solutions, as glycerol can enhance mucosal permeability and increase systemic exposure.
Use with caution: - Use cautiously with rectal medications that have a narrow therapeutic index, because altered absorption may affect drug levels. - Combine with other lubricants only under professional direction to prevent changes in osmotic balance. - When using with topical anesthetics, monitor for excessive numbness that may mask irritation.



