Europe — EMA
Glycerine Fagron Volwassenen (Glycerol)
Glycerine Fagron Volwassenen is an OTC rectal glycerol laxative for adult constipation, offering osmotic relief in the EU market.
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What is Glycerol?
Glycerine Fagron Volwassenen is an over‑the‑counter rectal preparation whose active ingredient is glycerol. It is supplied in a formulation designed for adult use and functions as an osmotic laxative to relieve occasional constipation. The product is marketed within the European Union and is classified as an excipient‑based laxative.
What is Glycerol used for?
Glycerine Fagron Volwassenen is indicated for the temporary relief of constipation in adults. It works by drawing water into the intestinal lumen, softening stool and facilitating bowel movements.
- Short‑term treatment of functional constipation - Adjunct to dietary measures for irregular bowel habits - Preparation for diagnostic procedures requiring bowel emptying - Use in patients where bulk‑forming agents are not tolerated - Management of constipation related to reduced mobility
What are the side effects of Glycerol?
Side effects of Glycerine Fagron Volwassenen are generally mild and related to its local action in the rectum.
Common: - Mild rectal irritation or burning sensation - Slight abdominal cramping - Loose stools or mild diarrhea - Transient urgency to defecate - Minor spotting of blood from hemorrhoidal tissue
Serious: - Severe rectal bleeding - Persistent abdominal pain - Signs of allergic reaction such as rash or swelling - Prolonged diarrhea leading to dehydration - Unexpected electrolyte imbalance
What precautions apply to Glycerol?
Before using Glycerine Fagron Volwassenen, consider the following precautions to ensure safe and effective use.
- Do not use if you have a known allergy to glycerol or any excipients. - Avoid in cases of intestinal obstruction, perforation, or severe inflammatory bowel disease. - Use with care in patients with hemorrhoids or anal fissures, as irritation may worsen. - Limit use to the recommended duration; prolonged use can lead to dependence on laxatives. - Consult a healthcare professional if constipation persists for more than a week. - Pregnant or breastfeeding individuals should seek medical advice before use.
What does Glycerol interact with?
Glycerine Fagron Volwassenen may interact with other medications or substances that affect bowel motility or electrolyte balance.
Avoid: - Concurrent use of strong stimulant laxatives, which may increase the risk of electrolyte disturbances. - Combining with medications that cause diarrhea, such as certain antibiotics or antidiarrheal agents.
Use with caution: - Anticoagulants, if rectal bleeding occurs. - Diuretic therapy, due to potential fluid loss from diarrhea. - Medications that require stable intestinal absorption, as altered transit time may affect efficacy. - Herbal supplements with laxative properties, such as senna or cascara.



