Europe — EMA
Glycerine Adultes Fagron (Glycerol)
Glycerine Adultes Faglon (glycerol) rectal preparation – uses, side effects, precautions, and interactions for safe therapeutic application.
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What is Glycerol?
Glycerine Adultes Faglon is a rectal preparation that contains glycerol as its sole active ingredient. It is supplied in an unspecified strength and dosage form intended for rectal administration. The product is manufactured in the European Union and is classified under the glycerol family, commonly used for its hygroscopic and lubricating properties in various therapeutic contexts.
What is Glycerol used for?
Glycerine Adultes Faglon is employed in several clinical situations where glycerol’s hygroscopic and lubricating actions are beneficial.
- Softening hard stools to facilitate bowel movements. - Acting as a mild rectal laxative for occasional constipation. - Providing local moisture to protect irritated rectal mucosa. - Serving as a component in enemas for bowel preparation. - Assisting in the removal of impacted feces under medical supervision.
What are the side effects of Glycerol?
Side effects of glycerol administered rectally are generally mild, but rare serious reactions can occur.
Common: - Mild rectal irritation or burning sensation. - Slight increase in bowel movement frequency. - Minor abdominal cramping. - Transient watery stools.
Serious: - Severe allergic reaction (rash, swelling, difficulty breathing). - Persistent rectal bleeding. - Prolonged diarrhea leading to dehydration. - Signs of electrolyte imbalance.
What precautions apply to Glycerol?
When using Glycerine Adultes Faglon, consider the following precautions to ensure safe use.
- Verify that the product is appropriate for the patient’s age and condition. - Avoid use in individuals with known hypersensitivity to glycerol. - Do not exceed recommended frequency; overuse may cause electrolyte disturbances. - Use caution in patients with inflammatory bowel disease or rectal lesions. - Consult a healthcare professional before use during pregnancy or lactation. - Keep the product out of reach of children.
What does Glycerol interact with?
Glycerine Adultes Faglon may interact with certain medications or substances when used rectally.
Avoid: - Concurrent use with strong stimulant laxatives, which may increase risk of dehydration. - Combining with oral osmotic agents without medical guidance.
Use with caution: - Antacids or medications that alter intestinal pH, potentially affecting glycerol absorption. - Diuretic therapy, due to possible additive fluid loss. - Electrolyte supplements, to monitor for imbalances. - Any systemic medication that may cause gastrointestinal irritation.



