Europe — EMA
Glucosteril (Glucose Monohydrate)
Glucosteril is a glucose monohydrate injection solution used in parenteral nutrition to provide carbohydrate energy intravenously.
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What is Glucose Monohydrate?
Glucosteril is a sterile solution for injection that contains glucose monohydrate as its active ingredient. It is supplied in an unspecified strength and is manufactured for the European Union market. The product is classified as an excipient used in parenteral nutrition, providing a source of carbohydrate energy when administered intravenously.
What is Glucose Monohydrate used for?
Glucosteril is employed as a component of intravenous nutrition regimens and as a source of rapid carbohydrate supplementation. It may be used in clinical settings where patients require energy support through the bloodstream.
- Supplemental carbohydrate source in total parenteral nutrition (TPN) - Energy provision during perioperative fasting - Management of hypoglycemia when oral intake is not possible - Support for patients with increased metabolic demand - Adjunct in fluid resuscitation protocols requiring caloric input
What are the side effects of Glucose Monohydrate?
Glucosteril is generally well tolerated, but adverse reactions can occur. Reported events are categorized by frequency and severity.
Common: - Local irritation at the injection site - Mild hyperglycemia - Transient electrolyte shifts - Nausea or vomiting - Headache
Serious: - Severe hyperglycemia leading to osmotic diuresis - Allergic reaction or anaphylaxis - Metabolic acidosis in susceptible patients - Fluid overload with pulmonary edema
What precautions apply to Glucose Monohydrate?
When using Glucosteril, clinicians should consider patient-specific factors and monitor relevant parameters to minimize risks.
- Assess blood glucose levels before and during infusion - Adjust dosage in patients with renal or hepatic impairment - Monitor for signs of fluid overload, especially in heart failure - Use caution in diabetic patients or those on insulin therapy - Verify compatibility with other intravenous solutions - Ensure aseptic technique to prevent infection - Document any adverse reactions promptly
What does Glucose Monohydrate interact with?
Glucosteril may interact with other medications or solutions administered intravenously. Awareness of these interactions helps maintain safety.
Avoid: - Co-administration with high‑dose insulin without glucose monitoring - Mixing with incompatible electrolytes that may precipitate - Simultaneous infusion of hypertonic dextrose solutions exceeding recommended concentrations
Use with caution: - Concurrent use of diuretics that affect fluid balance - Medications that alter glucose metabolism (e.g., glucocorticoids) - Intravenous lipid emulsions that may affect caloric calculations - Drugs that require strict electrolyte control (e.g., potassium‑sparing agents)



