Exzolt

Fluralaner, the active ingredient in Exzolt, is an isoxazoline ectoparasiticide presented as a chewable tablet for oral use. It provides systemic control of fleas and ticks in dogs, eliminating existing parasites and preventing new infestations. The product is formulated for convenient administration and is approved for use in the European Union.

GNH USA supplies Exzolt as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies, clinics, and veterinary hospitals worldwide, adhering to stringent quality standards and regulatory requirements through reliable logistics networks.

Exzolt (fluralaner) is an isoxazoline ectoparasiticide used to manage external parasite infestations in dogs.

- Flea infestation: eliminates adult fleas and interrupts the life cycle, providing rapid relief. - Tick infestation: kills attached ticks and prevents attachment of new ticks, reducing disease transmission risk. - Re‑infestation prevention: maintains continuous protection for up to 12 weeks, helping to keep dogs free from fleas and ticks.

Exzolt may be associated with a range of adverse reactions in treated animals.

Common Side Effects: - Vomiting: mild to moderate gastrointestinal upset. - Diarrhea: loose stools that usually resolve spontaneously. - Decreased appetite: temporary reduction in food intake. - Lethargy: mild fatigue or reduced activity. - Skin irritation: localized redness at the site of chewing. - Salivation: increased drooling after administration.

Serious or Rare Side Effects: - Seizures: neurological events requiring immediate veterinary attention. - Anaphylaxis: severe allergic reaction with swelling, hives, or respiratory distress. - Hepatic enzyme elevation: abnormal liver function tests. - Neutropenia: reduced white blood cell count. - Severe gastrointestinal ulceration: persistent vomiting or blood in stool. - Sudden death: extremely rare but reported in susceptible individuals.

When using Exzolt, follow veterinary guidance and observe the following precautions.

- Species restriction: use only in dogs as directed by a veterinarian. - Age limitation: do not administer to puppies younger than eight weeks. - Weight consideration: ensure the dog meets the minimum weight requirement for the selected dose. - Health status: avoid use in animals with known hypersensitivity to isoxazolines. - Concomitant ectoparasiticides: do not combine with other flea or tick products without veterinary approval. - Pregnancy and lactation: consult a veterinarian before use in breeding or lactating dogs. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Exzolt may interact with other medicines; monitor the following.

Major Interactions (Avoid): - Concurrent use with other isoxazoline ectoparasiticides: increased risk of neurotoxicity. - Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise systemic fluralaner levels. - Drugs that lower seizure threshold: potential for heightened neurologic events.

Moderate Interactions (Monitor Closely): - Oral anti‑inflammatory drugs: may affect gastrointestinal tolerance. - Vaccines: schedule administration at least 24 hours apart to avoid overlapping adverse reactions. - Food intake: high‑fat meals can delay absorption, requiring observation of efficacy.