GNH USA

USA — NDC

Exforge HCT 5 mg/1

GNH USA supplies Exforge HCT 5 mg/1 (Amlodipine Valsartan and Hydrochlorothiazide), a combination antihypertensive for hypertension.

Amlodipine Valsartan and Hydrochlorothiazide
Exforge HCT
TABLET, FILM COATED
5 mg/1

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1
Pack/s

What is Amlodipine Valsartan and Hydrochlorothiazide?

Amlodipine, valsartan, and hydrochlorothiazide, the active ingredients in Exforge HCT 5 mg/1, is a combination antihypertensive presented as a 5 mg/1 film-coated tablet for oral use. It is used to manage high blood pressure in patients whose blood pressure is not adequately controlled by two of the three components. GNH USA supplies Exforge HCT 5 mg/1 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Exforge HCT 5 mg/1 combines a calcium channel blocker, an angiotensin II receptor blocker, and a thiazide diuretic to provide a comprehensive approach to blood pressure management. This combination is designed to offer convenience and effectiveness for patients requiring multiple medications to control their hypertension.

What is Amlodipine Valsartan and Hydrochlorothiazide used for?

Exforge HCT 5 mg/1 is a combination antihypertensive medication used to manage high blood pressure (hypertension).

- Hypertension: Helps regulate blood pressure levels in patients whose blood pressure is not well controlled on any two of the three components (amlodipine, valsartan, or hydrochlorothiazide). - Cardiovascular health: Supports overall cardiovascular health by reducing the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. - Convenience: Provides a single-pill option for patients already taking all three medicines separately, simplifying their treatment regimen.

What are the side effects of Amlodipine Valsartan and Hydrochlorothiazide?

Exforge HCT 5 mg/1 may cause various side effects, ranging from common to serious or rare.

Common Side Effects: - Dizziness: May occur due to the blood pressure-lowering effect. - Fatigue: Commonly reported as the body adjusts to the medication. - Swelling in the legs or ankles: Caused by fluid retention or peripheral edema. - Headaches: May occur as a result of changes in blood pressure. - Nausea: A common gastrointestinal side effect. - Dry cough: Occasionally reported with valsartan use. - Muscle cramps: May occur due to electrolyte imbalances caused by hydrochlorothiazide. - Increased urination: Due to the diuretic effect of hydrochlorothiazide.

Serious or Rare Side Effects: - Hypotension: Excessive lowering of blood pressure, which can cause fainting or dizziness. - Hyperkalemia: High potassium levels in the blood, which can be dangerous for heart health. - Allergic reactions: Rare but can include rash, itching, or swelling. - Kidney problems: May occur due to the diuretic effect of hydrochlorothiazide. - Liver problems: Rare but can include jaundice or abnormal liver function tests. - Angioedema: Severe swelling of the face, lips, or tongue, which can be life-threatening.

What precautions apply to Amlodipine Valsartan and Hydrochlorothiazide?

Exforge HCT 5 mg/1 should be used with caution and under medical supervision. Patients with kidney or liver issues should handle this medication carefully. Avoid sudden discontinuation without medical guidance. Common effects may include dizziness, fatigue, and swelling in the legs or ankles. Always consult a healthcare provider for personalized advice.

- Handle with care: Especially if you have kidney or liver issues. - Avoid sudden discontinuation: Without medical guidance. - Store at room temperature: Away from moisture and heat. - Follow prescribed usage: Monitor for any adverse reactions. - Inform healthcare provider: About all medications you are taking to avoid potential interactions. - Store below 25°C: Keep in the original pack, protect from moisture.

What does Amlodipine Valsartan and Hydrochlorothiazide interact with?

Exforge HCT 5 mg/1 may interact with other medications, potentially altering its effectiveness or increasing the risk of side effects.

Major Interactions (Avoid): - Alcohol: Can enhance the blood pressure-lowering effect, leading to excessive dizziness or fainting. - Other blood pressure medications: May cause additive effects, leading to hypotension. - Certain pain relievers: Such as nonsteroidal anti-inflammatory drugs (NSAIDs), which can reduce the effectiveness of Exforge HCT. - CYP inhibitors: Drugs that affect liver enzymes, altering the metabolism of Exforge HCT. - Potassium-sparing diuretics: Can increase the risk of hyperkalemia.

Moderate Interactions (Monitor Closely): - Lithium: Can increase the risk of lithium toxicity. - Digoxin: May increase the risk of digoxin toxicity. - Antidiabetic medications: May require dose adjustment due to changes in blood pressure. - Corticosteroids: Can reduce the effectiveness of Exforge HCT. - Anticholinergic drugs: May increase the risk of dry mouth and constipation.

Frequently asked questions

What is Exforge HCT 5 mg/1 used for?+
Exforge HCT 5 mg/1 is used to manage high blood pressure (hypertension) in patients whose blood pressure is not adequately controlled by two of the three components (amlodipine, valsartan, or hydrochlorothiazide). It combines a calcium channel blocker, an angiotensin II receptor blocker, and a thiazide diuretic to provide a comprehensive approach to blood pressure management.
How does Exforge HCT 5 mg/1 work?+
Exforge HCT 5 mg/1 works through the combined actions of its three active ingredients. Amlodipine relaxes vascular smooth muscle by inhibiting calcium influx, leading to vasodilation. Valsartan blocks angiotensin II type 1 receptors, preventing vasoconstriction and reducing blood pressure. Hydrochlorothiazide promotes diuresis by inhibiting sodium chloride reabsorption in the distal convoluted tubule, reducing blood volume and lowering blood pressure.
What is the usual dose of Exforge HCT 5 mg/1?+
The usual dose of Exforge HCT 5 mg/1 is determined by a healthcare provider based on the patient's individual needs and response to the medication. It is typically taken once daily, but the specific dosage and regimen should be followed as prescribed by the healthcare provider.
Is Exforge HCT 5 mg/1 safe during pregnancy or breastfeeding?+
The safety of Exforge HCT 5 mg/1 during pregnancy or breastfeeding has not been established. It is important to consult a healthcare provider before taking this medication if you are pregnant, planning to become pregnant, or breastfeeding. The healthcare provider can provide personalized advice based on the potential benefits and risks.
How do I order Exforge HCT 5 mg/1 from GNH USA?+
To order Exforge HCT 5 mg/1 from GNH USA, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the import paperwork.
How does Exforge HCT 5 mg/1 compare to other blood pressure medications?+
Exforge HCT 5 mg/1 is a combination medication that offers the convenience of taking three blood pressure medications in a single pill. It is particularly useful for patients whose blood pressure is not adequately controlled by two of the three components. Compared to other blood pressure medications, Exforge HCT 5 mg/1 provides a comprehensive approach to blood pressure management by targeting multiple pathways involved in hypertension.
How should Exforge HCT 5 mg/1 be stored and handled?+
Exforge HCT 5 mg/1 should be stored at room temperature, away from moisture and heat. It is important to keep the medication in its original packaging and protect it from light. Always follow the storage instructions provided by the manufacturer and consult a healthcare provider if you have any questions about storage and handling.
How is Exforge HCT 5 mg/1 administered?+
Exforge HCT 5 mg/1 is taken orally, typically once daily. The tablet should be swallowed whole with a glass of water, with or without food. It is important to follow the dosage and administration instructions provided by the healthcare provider to ensure the best results.
What are the most serious risks to watch for with Exforge HCT 5 mg/1?+
The most serious risks to watch for with Exforge HCT 5 mg/1 include hypotension (excessive lowering of blood pressure), hyperkalemia (high potassium levels in the blood), allergic reactions, kidney problems, liver problems, and angioedema (severe swelling of the face, lips, or tongue). Patients should seek immediate medical attention if they experience any of these serious side effects.
Who should not use Exforge HCT 5 mg/1?+
Exforge HCT 5 mg/1 should not be used by patients who are allergic to any of its active ingredients (amlodipine, valsartan, or hydrochlorothiazide) or any of the inactive ingredients in the formulation. It should also be used with caution in patients with kidney or liver issues, and under medical supervision. Always consult a healthcare provider before starting this medication.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Amlodipine Valsartan and Hydrochlorothiazide
Brand
Exforge HCT
Strength
5 mg/1
Form
TABLET, FILM COATED
Route
ORAL
Pack size
30 TABLET, FILM COATED in 1 BOTTLE (0078-0559-15)
Manufacturer
Novartis Pharmaceuticals Corporation
Origin
USA

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