GNH USA

Europe — EMA

Mikronizované Flavonoidy (Diosmin)

GNH USA supplies Mikronizované Flavonoidy (Diosmin), a flavonoid vasoprotective agent for chronic venous insufficiency and hemorrhoids.

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What is Diosmin?

Diosmin, the active ingredient in Mikronizované Flavonoidy, is a flavonoid (vasoprotective agent) presented as a micronized oral formulation for oral use. It is employed to support vascular health in adults with chronic venous insufficiency and hemorrhoidal disease.

GNH USA supplies Mikronizované Flavonoidy as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Diosmin used for?

Mikronizované Flavonoidy acts on the venous and microcirculatory system to improve vascular tone and reduce edema. - Chronic venous insufficiency: enhances venous return and lessens leg heaviness and swelling. - Hemorrhoidal disease: decreases venous congestion, reducing bleeding and discomfort. - Varicose veins: supports reduction of leg pain, edema and improves overall limb comfort.

What are the side effects of Diosmin?

Mikronizované Flavonoidy is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Gastrointestinal discomfort: mild abdominal pain or upset stomach. - Nausea: occasional feeling of queasiness. - Headache: transient mild headache. - Dizziness: light‑headed sensation.

Serious or Rare Side Effects: - Severe allergic reaction: rash, swelling, difficulty breathing. - Hepatic dysfunction: elevated liver enzymes or jaundice. - Thrombocytopenia: unusually low platelet count.

What precautions apply to Diosmin?

Before initiating therapy, consider the following precautions. - Renal or hepatic impairment: assess function and monitor periodically. - Bleeding disorders: use with caution due to potential impact on coagulation. - Known hypersensitivity: avoid if allergic to flavonoids. - Pregnancy and lactation: safety not established; consult a healthcare professional. - Do not exceed prescribed amount: follow prescriber instructions. - Store at ambient temperature: keep in the original pack, protect from moisture.

What does Diosmin interact with?

Diosmin may interact with several medication classes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - NSAIDs: additive gastrointestinal irritation.

Moderate Interactions (Monitor Closely): - Antihypertensives: possible additive blood‑pressure lowering effect. - Antiplatelet agents: enhanced antithrombotic activity. - Oral contraceptives: potential alteration of hormone metabolism.

Frequently asked questions

What is Mikronizované Flavonoidy used for?+
Mikronizované Flavonoidy is used to support vascular health in adults with chronic venous insufficiency, varicose veins and hemorrhoidal disease. The micronized diosmin formulation helps improve venous tone, reduce leg swelling and alleviate hemorrhoid‑related bleeding and discomfort.
How does Diosmin work?+
Diosmin acts as a venotonic agent. It increases the contractility of venous smooth muscle, lowers venous capacitance, and promotes lymphatic drainage. By stabilising capillary permeability, it improves microcirculation and reduces edema in the affected vascular beds.
What is the usual dose of Mikronizované Flavonoidy?+
The dosage of Mikronizované Flavonoidy is determined by the prescribing healthcare professional based on the individual’s condition, severity and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.
Is Mikronizované Flavonoidy safe during pregnancy or breastfeeding?+
Safety data for diosmin in pregnancy and lactation are limited. It is classified as a precautionary medication, and use should only be considered if the potential benefit justifies any possible risk. Consultation with a qualified healthcare provider is essential before use.
How do I order Mikronizované Flavonoidy from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Mikronizované Flavonoidy compare with other venoprotective agents?+
Mikronizované Flavonoidy (diosmin) is comparable to other flavonoid‑based agents such as hesperidin or horse‑chestnut extract. Diosmin offers a well‑studied venotonic profile with a favorable safety record, while combination products may provide additional synergistic effects. Choice of therapy depends on clinical judgment, patient tolerance and regional guidelines.
How should Mikronizované Flavonoidy be stored and handled?+
Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging to protect it from moisture and light. Do not expose the tablets or granules to excessive heat or humidity, and keep them out of reach of children.
How is Mikronizované Flavonoidy administered?+
Mikronizované Flavonoidy is taken orally, usually with a glass of water. It can be taken with or without food, unless the prescriber advises otherwise. Swallow the tablets or granules whole; do not crush or chew unless specifically instructed.
What are the most serious risks associated with Mikronizované Flavonoidy?+
Serious adverse reactions, although rare, include severe allergic responses such as rash, swelling or breathing difficulty, hepatic dysfunction manifested by elevated liver enzymes or jaundice, and thrombocytopenia leading to abnormal bleeding. Patients should seek immediate medical attention if any of these symptoms develop.
Who should not use Mikronizované Flavonoidy?+
Individuals with known hypersensitivity to diosmin or other flavonoids should avoid the product. It is also contraindicated in patients with severe liver disease, uncontrolled bleeding disorders, or those who are pregnant or breastfeeding unless the prescriber determines that the benefits outweigh the risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Diosmin
Route
Oral Use
Manufacturer
Stada Arzneimittel Ag
Origin
EU

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