Dicloflex

Dicloflex is a topical medication that contains the non‑steroidal anti‑inflammatory drug (NSAID) diclofenac sodium. It is formulated for cutaneous application and is marketed in the European Union. The product delivers diclofenac sodium through the skin to provide localized analgesic and anti‑inflammatory effects without systemic administration. It is intended for short‑term use on intact skin over painful joints or muscles, and it is supplied without a prescription in many EU countries.

Dicloflex is applied to the skin to manage localized pain and inflammation associated with musculoskeletal conditions.

- Relief of mild to moderate pain from osteoarthritis of the knee or other joints. - Reduction of inflammation and discomfort from sprains, strains, and bruises. - Management of tendonitis or bursitis symptoms in the affected area. - Adjunctive therapy for postoperative or post‑traumatic pain where oral NSAIDs are unsuitable. - Temporary relief of back or shoulder muscle aches.

Topical diclofenac may cause skin‑related and systemic side effects, most of which are mild and reversible.

Common: - Local skin irritation, redness, or itching at the application site. - Burning or stinging sensation shortly after application. - Dryness or peeling of the treated skin. - Mild headache.

Serious: - Allergic skin reactions such as rash, hives, or swelling. - Severe skin ulceration or necrosis. - Signs of systemic NSAID toxicity (e.g., gastrointestinal bleeding, dizziness). - Liver enzyme elevation or hepatic dysfunction.

When using Dicloflex, certain precautions help minimize risks and ensure safe use.

- Apply only to intact, unbroken skin and avoid mucous membranes. - Do not cover the treated area with occlusive dressings unless directed by a healthcare professional. - Limit use to the recommended duration, typically not exceeding 7‑10 days without medical advice. - Avoid use on large body surface areas to reduce systemic absorption. - Discontinue if signs of allergic reaction or severe skin irritation develop. - Consult a physician before use in patients with known cardiovascular, renal, or hepatic disease. - Keep out of reach of children; accidental ingestion may cause systemic NSAID effects.

Dicloflex can interact with other medicines, especially those that affect bleeding, kidney function, or systemic NSAID exposure.

Avoid: - Concurrent use of oral or injectable NSAIDs, aspirin, or anticoagulants (e.g., warfarin, clopidogrel) that increase bleeding risk. - Systemic corticosteroids or other anti‑inflammatory agents that may heighten gastrointestinal toxicity. - Other topical products containing diclofenac or similar NSAIDs, which could raise total diclofenac exposure.

Use with caution: - Diuretics or ACE inhibitors in patients with renal impairment, as NSAIDs can affect kidney function. - Lithium therapy, because NSAIDs may increase lithium serum levels. - Methotrexate, as NSAIDs can reduce its clearance. - Antihypertensive medications, where NSAIDs might blunt their effect.