Citrafleet

Citrafleet is an oral bowel preparation containing sodium picosulfate, magnesium oxide, and citric acid. The product is supplied in tablet form, with strength not publicly disclosed, and is marketed in the European Union for colon cleansing before diagnostic procedures. It belongs to the laxative drug class and works by stimulating colonic peristalsis and increasing intestinal water content, facilitating effective bowel evacuation.

Citrafleet is indicated for bowel cleansing in preparation for gastrointestinal examinations and procedures.

- Colonoscopy preparation - Flexible sigmoidoscopy preparation - Radiographic imaging of the colon (e.g., barium enema) - Pre‑operative bowel preparation for colorectal surgery - Other diagnostic tests requiring a clean colon

The most frequently reported effects of Citrafleet are related to its laxative action, while rare but serious reactions may also occur.

Common: - Abdominal cramping - Diarrhea - Nausea - Flatulence - Thirst - Mild electrolyte imbalance

Serious: - Severe dehydration - Persistent vomiting - Blood in stool - Allergic skin rash - Signs of electrolyte disturbance such as muscle weakness

Before using Citrafleet, certain precautions should be considered to ensure safety and effectiveness.

- Confirm normal kidney function - Avoid use in patients with severe constipation or bowel obstruction - Do not use if allergic to any component - Discuss with a physician if taking other laxatives or diuretics - Ensure adequate fluid intake during preparation - Pregnant or breastfeeding women should consult a healthcare professional - Hold the dose if experiencing severe abdominal pain

Citrafleet may interact with other medicines, influencing its efficacy or safety.

Avoid: - Concomitant use with other strong or stimulant laxatives - Use with medications that may cause electrolyte disturbances (e.g., digitalis, certain antihypertensives) - Concurrent use with oral potassium supplements without monitoring

Use with caution: - Diuretics - Antacids containing magnesium or aluminum - Certain antibiotics that require optimal intestinal absorption - Medications with a narrow therapeutic index that are affected by fluid shifts