CHANTIX 1 mg/1

Varenicline, the active ingredient in CHANTIX, is a partial agonist of α4β2 nicotinic acetylcholine receptors presented as a 1 mg film-coated tablet for oral use. It is indicated for smoking cessation in adults.

GNH USA supplies CHANTIX as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

CHANTIX is a smoking cessation aid that helps reduce nicotine cravings and withdrawal symptoms.

- Smoking cessation: Helps adults quit smoking by reducing cravings and withdrawal symptoms. - Smoking reduction: For patients who are not ready to quit abruptly, it can help gradually reduce smoking habits over time. - Long-term abstinence: Recommended for an additional 12 weeks after initial treatment to increase the likelihood of sustained smoking cessation.

CHANTIX can cause various side effects, ranging from mild to severe.

Common Side Effects: - Nausea: Often mild or moderate and may be transient. - Headache: Common but usually manageable. - Vomiting: Can occur, especially during the initial stages of treatment. - Insomnia: Difficulty sleeping may be experienced. - Abnormal dreams: Vivid or unusual dreams are reported. - Dizziness: Some patients may experience lightheadedness. - Constipation: Can occur as a side effect. - Dry mouth: A common but usually mild side effect.

Serious or Rare Side Effects: - Mood changes: Including depression, anxiety, and agitation. - Suicidal thoughts: Rare but serious, requiring immediate medical attention. - Seizures: Rare but possible, especially in patients with a history of seizures. - Allergic reactions: Such as rash, itching, or swelling, which require immediate medical attention.

CHANTIX should be used with caution and under medical supervision.

- Prescription use: Only use CHANTIX as prescribed by a healthcare provider. - Mental health monitoring: Regularly monitor for changes in mood or behavior. - Seizure history: Use with caution in patients with a history of seizures. - Renal impairment: Adjust dosage for patients with severe renal impairment. - Pregnancy: Consult a healthcare provider before use during pregnancy. - Breastfeeding: Consult a healthcare provider before use while breastfeeding. - Store below 25°C: Keep in the original pack, protect from moisture.

CHANTIX can interact with other medications, potentially affecting its efficacy or increasing the risk of side effects.

Major Interactions (Avoid): - Nicotine replacement therapy: Avoid concurrent use to prevent adverse effects. - Bupropion: Avoid concurrent use due to increased risk of seizures. - Insulin: Monitor blood glucose levels closely when starting or stopping CHANTIX.

Moderate Interactions (Monitor Closely): - Antidepressants: Monitor for increased risk of mood changes. - Antipsychotics: Monitor for increased risk of side effects. - Alcohol: Monitor for increased risk of side effects such as dizziness and drowsiness.