Cevimeline Hydrochloride 30 mg/1

Cevimeline hydrochloride, the active ingredient in cevimeline hydrochloride, is a muscarinic cholinergic agonist presented as a 30 mg capsule for oral use. It is used to treat symptoms of dry mouth in patients with Sjögren’s syndrome, a condition that affects the immune system and causes dryness in certain parts of the body such as the eyes and mouth.

GNH USA supplies cevimeline hydrochloride as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Cevimeline hydrochloride is a muscarinic cholinergic agonist used to treat symptoms of dry mouth in patients with Sjögren’s syndrome. It works by stimulating certain nerves to increase the amount of saliva produced, making it easier and more comfortable to speak and swallow.

- Sjögren’s syndrome: Treats dry mouth (xerostomia) by stimulating salivary gland secretion. - Radiation-induced xerostomia: May be used to alleviate dry mouth caused by radiation therapy.

Cevimeline hydrochloride may cause side effects, which can vary in severity. Common side effects include mild to moderate symptoms, while serious or rare side effects are less frequent but more severe.

Common Side Effects: - Sweating - Nausea - Runny nose (rhinitis) - Flushing - Frequent urge to urinate - Dizziness - Weakness - Diarrhea - Blurred vision

Serious or Rare Side Effects: - Extreme fatigue - Irregular heartbeat - Swelling - Severe diarrhea - Severe blurred vision - Severe nausea or vomiting

Cevimeline hydrochloride should be used with caution in certain populations and conditions. It is important to follow the prescribed dosage and consult with a healthcare provider for personalized advice.

- Heart conditions: Use with caution in patients with heart disease, as it may affect heart rate or rhythm. - Asthma: Avoid use in patients with uncontrolled asthma, as it can increase airway secretions and resistance. - Glaucoma: Use with caution in patients with narrow-angle (angle-closure) glaucoma, as it can narrow the pupil. - Pregnancy: Safety in pregnancy is unknown; consult a healthcare provider before use. - Breastfeeding: Safety during breastfeeding is unknown; consult a healthcare provider before use. - Storage: Store at room temperature away from light and moisture. Keep out of reach of children.

Cevimeline hydrochloride may interact with other medications, which can affect its efficacy or increase the risk of side effects. It is important to inform your healthcare provider about all medications you are taking.

Major Interactions (Avoid): - Beta-blockers: May interact with cevimeline hydrochloride, affecting heart rate or blood pressure. - Anticholinergic drugs: May reduce the effectiveness of cevimeline hydrochloride.

Moderate Interactions (Monitor Closely): - Drugs that affect heart rate: May require monitoring when used with cevimeline hydrochloride. - Drugs that affect blood pressure: May require monitoring when used with cevimeline hydrochloride. - Drugs that affect gastrointestinal motility: May require monitoring when used with cevimeline hydrochloride.