GNH USA

Europe — EMA

Levodopa/Carbidopa/Entacaponă Teva

GNH USA supplies Levodopa/Carbidopa/Entacaponă Teva (Levodopa/Carbidopa/Entacapone), a antiparkinson agent for Parkinson's disease. Request quote for supply.

Carbidopa, Entacapone, Levodopa

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What is Carbidopa, Entacapone, Levodopa?

Levodopa, Carbidopa and Entacapone, the active ingredients in Levodopa/Carbidopa/Entacaponă Teva, are antiparkinson agents presented as an oral tablet for oral use. They treat Parkinson's disease by restoring dopaminergic activity in patients with the condition.

GNH USA supplies Levodopa/Carbidopa/Entacaponă Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Carbidopa, Entacapone, Levodopa used for?

Levodopa/Carbidopa/Entacapone is used in the management of Parkinson's disease, targeting dopaminergic pathways.

Parkinson's disease: improves motor symptoms, reduces OFF time and enhances daily functional ability.

What are the side effects of Carbidopa, Entacapone, Levodopa?

Levodopa/Carbidopa/Entacapone may cause a range of adverse reactions.

Common Side Effects: - Nausea or vomiting - Dizziness or light‑headedness - Orthostatic hypotension - Insomnia or vivid dreams - Headache - Dry mouth

Serious or Rare Side Effects: - Dyskinesia or uncontrolled movements - Hallucinations or psychosis - Severe hypotension or syncope - Neuroleptic malignant syndrome - Cardiac arrhythmias - Anaphylactic or severe allergic reactions

What precautions apply to Carbidopa, Entacapone, Levodopa?

Before initiating therapy, clinicians should consider several safety aspects. - Renal or hepatic impairment: adjust dose and monitor function - Cardiovascular disease: watch for hypotension and arrhythmias - History of psychiatric disorders: monitor for hallucinations or mood changes - Pregnancy and lactation: safety not established, use only if essential - Concomitant MAO‑B inhibitors: avoid combined use - Store at ambient temperature: keep in original packaging, protect from moisture.

What does Carbidopa, Entacapone, Levodopa interact with?

Levodopa/Carbidopa/Entacapone can interact with several drug classes.

Major Interactions (Avoid): - Non‑selective MAO inhibitors: risk of hypertensive crisis - Antipsychotics that block dopamine receptors: may reduce efficacy - High‑dose pyridoxine (vitamin B6): can accelerate levodopa metabolism

Moderate Interactions (Monitor Closely): - Selective MAO‑B inhibitors: may increase levodopa levels - Antihypertensive agents: additive blood‑pressure lowering effect - Anticholinergics: may mask anticholinergic toxicity - Iron or calcium supplements: reduce levodopa absorption if taken simultaneously - High‑protein meals: compete with levodopa for intestinal transport

Frequently asked questions

What is Levodopa/Carbidopa/Entacaponă Teva used for?+
Levodopa/Carbidopa/Entacaponă Teva is a combination medication prescribed to manage the motor symptoms of Parkinson's disease. It works by increasing dopamine levels in the brain, helping to reduce tremor, rigidity, and bradykinesia in patients diagnosed with this neurodegenerative disorder.
How does the combination of levodopa, carbidopa and entacapone work?+
Levodopa is a dopamine precursor that crosses the blood‑brain barrier and is converted to dopamine. Carbidopa blocks peripheral decarboxylation of levodopa, allowing more of the drug to reach the brain. Entacapone inhibits the COMT enzyme, slowing levodopa breakdown and prolonging its therapeutic effect.
What is the usual dose of Levodopa/Carbidopa/Entacaponă?+
The dosage of Levodopa/Carbidopa/Entacaponă is individualized. A qualified prescriber determines the appropriate strength, frequency and total daily dose based on the patient’s disease stage, response to therapy and tolerability. Patients should follow the prescribing information provided by their healthcare professional.
Is Levodopa/Carbidopa/Entacaponă safe during pregnancy or breastfeeding?+
Safety data for Levodopa/Carbidopa/Entacaponă in pregnancy and lactation are limited. The product is classified as having an unknown pregnancy category, and it should only be used if the potential benefit justifies any possible risk to the fetus or infant. Consultation with a specialist is essential.
How do I order Levodopa/Carbidopa/Entacaponă from GNH USA?+
To place an order, visit the product page on gnh-usa.com, submit an enquiry with the required quantity, and provide institutional or trade credentials. GNH USA’s team will verify the information, then respond with pricing, availability, shipping details and any necessary import documentation.
How does Levodopa/Carbidopa/Entacaponă compare with other Parkinson’s medications?+
Compared with levodopa alone, the addition of carbidopa reduces peripheral side effects and increases central availability, while entacapone further extends levodopa’s half‑life. This triple combination often provides smoother symptom control and fewer motor fluctuations than single‑component regimens.
What are the storage and handling requirements for this product?+
Levodopa/Carbidopa/Entacaponă tablets should be stored at ambient temperature, below 25 °C, in the original blister pack. Keep the container tightly closed, protect from moisture and direct sunlight, and discard any tablets that appear discolored or damaged.
How is Levodopa/Carbidopa/Entacaponă administered?+
The medication is taken orally, usually with a glass of water. It can be taken with or without food, but consistent timing relative to meals helps maintain stable plasma levels. Patients should swallow the tablets whole and avoid crushing or chewing them unless directed otherwise.
What are the most serious risks associated with this therapy?+
Serious risks include dyskinesia (involuntary movements), hallucinations or psychosis, severe orthostatic hypotension, and rare cases of neuroleptic malignant syndrome. Prompt medical attention is required if any of these symptoms develop, as they may indicate the need for dose adjustment or discontinuation.
Who should not use Levodopa/Carbidopa/Entacaponă?+
Patients with known hypersensitivity to levodopa, carbidopa, entacapone or any excipients should avoid this product. It is also contraindicated in individuals taking non‑selective MAO inhibitors or those with a history of malignant neuroleptic syndrome. Clinicians must evaluate each patient’s medical history before prescribing.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Carbidopa, Entacapone, Levodopa
Route
Oral Use
Manufacturer
Teva Pharmaceuticals S.R.L
Origin
EU

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