GNH USA

USA — NDC

Buprenorphine 2 mg/1

GNH USA supplies Buprenorphine (Buprenorphine), a partial opioid agonist for opioid use disorder and chronic pain. Request a quote for global supply.

Buprenorphine
Buprenorphine
TABLET
2 mg/1

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1
Pack/s

What is Buprenorphine?

Buprenorphine, the active ingredient in Buprenorphine, is a partial opioid agonist presented as a 2 mg/tablet for sublingual use. It is used to treat moderate to severe chronic pain and opioid dependence. GNH USA supplies Buprenorphine as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Buprenorphine is a well-established medication for managing opioid use disorder and chronic pain. Its unique pharmacological profile makes it a valuable tool in addiction treatment and pain management.

What is Buprenorphine used for?

Buprenorphine is used to manage opioid use disorder and moderate to severe chronic pain. It helps by:

- Opioid dependence treatment: Reduces withdrawal symptoms and cravings for opioids. - Chronic pain management: Provides analgesia for moderate to severe pain. - Opioid overdose prevention: Lowers the risk of overdose due to its ceiling effect on respiratory depression. - Maintenance therapy: Supports long-term recovery from opioid addiction. - Harm reduction: Helps individuals stabilize and reduce the harmful effects of opioid use.

What are the side effects of Buprenorphine?

Buprenorphine can cause various side effects, ranging from common to serious. Common Side Effects: - Nausea and vomiting - Constipation - Headache - Sweating - Dizziness - Insomnia - Fatigue

Serious or Rare Side Effects: - Respiratory depression - Allergic reactions - Liver toxicity - Hormonal imbalances - Dependence and abuse potential - Withdrawal symptoms upon discontinuation

What precautions apply to Buprenorphine?

Buprenorphine should be used with caution and under medical supervision. Important precautions include: - Pregnancy: Use with caution, as it may affect the newborn. - Breastfeeding: Consult a healthcare provider before use. - Driving: Avoid operating heavy machinery until the effects are known. - Alcohol: Avoid alcohol consumption to prevent increased sedation. - Other medications: Inform your doctor about all medications you are taking. - Storage: Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F).

What does Buprenorphine interact with?

Buprenorphine can interact with other medications, potentially altering its effects or increasing the risk of side effects. Major Interactions (Avoid): - Other opioids: Can increase the risk of respiratory depression. - Benzodiazepines: Can cause severe sedation and respiratory depression. - Alcohol: Can enhance the sedative effects of buprenorphine. - MAO inhibitors: Can increase the risk of serotonin syndrome.

Moderate Interactions (Monitor Closely): - Antidepressants: May increase the risk of side effects. - Antipsychotics: Can enhance the sedative effects of buprenorphine. - Antihistamines: May increase drowsiness.

Frequently asked questions

What is Buprenorphine used for?+
Buprenorphine is used to treat opioid use disorder and moderate to severe chronic pain. It helps reduce withdrawal symptoms and cravings for opioids, making it a valuable tool in addiction treatment and pain management.
How does Buprenorphine work?+
Buprenorphine acts as a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor. This dual action provides analgesia while limiting the risk of respiratory depression, a common side effect of full opioid agonists.
What is the usual dosage of Buprenorphine?+
The usual starting dosage of Buprenorphine ranges from 2 to 8 mg once per day. The dosage is adjusted by the prescriber based on the individual's response and needs, with a recommended target dosage of 16 mg once per day for long-term treatment.
Is Buprenorphine safe during pregnancy or breastfeeding?+
Buprenorphine should be used with caution during pregnancy and breastfeeding. It may affect the newborn, and its use should be carefully monitored by a healthcare provider.
How do I order Buprenorphine from GNH USA?+
To order Buprenorphine from GNH USA, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.
How does Buprenorphine compare to other opioid treatments?+
Buprenorphine has a lower risk of respiratory depression compared to full opioid agonists like morphine and oxycodone. Its ceiling effect makes it safer for long-term use and reduces the risk of overdose.
How should Buprenorphine be stored and handled?+
Buprenorphine should be stored at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep it out of reach of children and pets, and dispose of any unused medication properly.
How is Buprenorphine administered?+
Buprenorphine is typically administered as a sublingual tablet, which is placed under the tongue and allowed to dissolve. It is usually taken once per day as directed by a healthcare provider.
What are the most serious risks associated with Buprenorphine?+
The most serious risks associated with Buprenorphine include respiratory depression, allergic reactions, liver toxicity, and the potential for dependence and abuse. It is important to use Buprenorphine under medical supervision.
Who should not use Buprenorphine?+
Buprenorphine should not be used by individuals with severe respiratory depression, acute asthma, or a known hypersensitivity to buprenorphine. It should be used with caution in individuals with liver disease, head injuries, or a history of substance abuse.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Buprenorphine
Brand
Buprenorphine
Strength
2 mg/1
Form
TABLET
Route
SUBLINGUAL
Pack size
30 TABLET in 1 BOTTLE (0054-0176-13)
Manufacturer
Hikma Pharmaceuticals USA Inc.
Origin
USA

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