GNH USA

USA — NDC

Arestin Microspheres 1 mg

GNH USA supplies Arestin 1 mg (Minocycline), a tetracycline antibiotic for the treatment of periodontal disease. Request a quote for global supply.

Minocycline (Minocycline Hydrochloride)
ARESTIN MICROSPHERES
POWDER (EXTENDED RELEASE)
1 MG

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1
Pack/s

What is Minocycline (Minocycline Hydrochloride)?

Minocycline, the active ingredient in Arestin Microspheres 1 mg, is a tetracycline antibiotic presented as a 1 mg powder for extended-release microspheres for subgingival use. It is indicated as an adjunct to scaling and root planing (SRP) procedures for the reduction of pocket depth in patients with adult periodontitis.

GNH USA supplies Arestin Microspheres 1 mg as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

What is Minocycline (Minocycline Hydrochloride) used for?

Arestin Microspheres 1 mg is a tetracycline antibiotic used in the management of periodontal disease. It is designed for localized application in dental care, delivering medication directly to the affected areas.

- Adult periodontitis: Reduces pocket depth as an adjunct to scaling and root planing procedures. - Periodontal pockets: Targets and reduces bacteria in the gums to manage infections. - Chronic periodontal disease: Aids in the conservative treatment of chronic periodontal disease prior to surgery.

What are the side effects of Minocycline (Minocycline Hydrochloride)?

Arestin Microspheres 1 mg may cause various side effects, ranging from common to serious or rare.

Common Side Effects: - Localized discomfort or sensitivity at the application site. - Mild irritation or swelling around the treated area. - Temporary discomfort during or after administration. - Headache. - Infection. - Flu symptoms. - Pain.

Serious or Rare Side Effects: - Allergic reactions, such as rash, itching, or swelling. - Severe irritation or prolonged swelling at the application site. - Signs of infection that worsen or do not improve.

What precautions apply to Minocycline (Minocycline Hydrochloride)?

Arestin Microspheres 1 mg should be used with caution and under the guidance of a dental professional. Important precautions include:

- Allergies: Inform your dental professional if you are allergic to minocycline or tetracyclines. - Pregnancy: Avoid use during pregnancy as it may cause permanent discoloration of the teeth in developing fetuses. - Breastfeeding: Avoid use while breastfeeding due to potential risks to the infant. - Children: Not recommended for use in children due to the risk of tooth discoloration. - Weakened immune systems: Has not been studied in patients with weakened immune systems, such as those with HIV infections or diabetes. - Store at room temperature: Keep in a cool, dry place and follow the storage instructions provided.

What does Minocycline (Minocycline Hydrochloride) interact with?

Arestin Microspheres 1 mg may interact with other medications, requiring careful monitoring or avoidance.

Major Interactions (Avoid): - Tetracycline-class drugs: Avoid concurrent use with other tetracycline-class antibiotics to prevent increased side effects. - Antacids: Avoid taking antacids within 2 hours of administration to prevent reduced effectiveness. - Dairy products: Avoid consuming dairy products within 2 hours of administration to prevent reduced absorption.

Moderate Interactions (Monitor Closely): - Oral contraceptives: Monitor for reduced effectiveness of oral contraceptives when used concurrently. - Warfarin: Monitor for increased anticoagulant effects when used concurrently. - Methoxyflurane: Monitor for increased risk of nephrotoxicity when used concurrently.

Frequently asked questions

What is Arestin Microspheres 1 mg used for?+
Arestin Microspheres 1 mg is used as an adjunct to scaling and root planing (SRP) procedures for the reduction of pocket depth in patients with adult periodontitis. It is a subgingival extended-release powder containing minocycline hydrochloride, which is applied directly into the periodontal pockets to manage bacterial infections in the gums.
How does minocycline work in Arestin Microspheres 1 mg?+
Minocycline, the active ingredient in Arestin Microspheres 1 mg, inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. This prevents the attachment of aminoacyl-tRNA, thereby halting bacterial growth and replication. The extended-release formulation ensures sustained delivery of the antibiotic directly to the infection site, enhancing its efficacy in managing periodontal disease.
What is the usual dose of Arestin Microspheres 1 mg?+
The dose of Arestin Microspheres 1 mg is determined by a dental professional based on the individual needs of the patient. Each cartridge contains 1 mg of minocycline hydrochloride and is designed for a single application into a periodontal pocket. The prescriber will determine the appropriate dosage and administration schedule.
Is Arestin Microspheres 1 mg safe during pregnancy or breastfeeding?+
Arestin Microspheres 1 mg should be avoided during pregnancy and breastfeeding. The use of tetracycline-class drugs, including minocycline, during tooth development may cause permanent discoloration of the teeth. Therefore, it is not recommended for use in pregnant or breastfeeding women.
How do I order Arestin Microspheres 1 mg from GNH USA?+
To order Arestin Microspheres 1 mg from GNH USA, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the necessary import paperwork.
How does Arestin Microspheres 1 mg compare to other periodontal treatments?+
Arestin Microspheres 1 mg is a locally applied antibiotic that delivers a concentrated dose directly to the base of the periodontal pocket. Unlike systemic antibiotics, it targets the infection site specifically, reducing the risk of systemic side effects. It is also bioresorbable, meaning it does not require removal after administration, making it a convenient option for periodontal treatment.
How should Arestin Microspheres 1 mg be stored and handled?+
Arestin Microspheres 1 mg should be stored at room temperature in a cool, dry place. It is important to follow the storage instructions provided to maintain the effectiveness of the medication. The medication should be handled with care to avoid contamination and should be kept out of reach of children.
How is Arestin Microspheres 1 mg administered?+
Arestin Microspheres 1 mg is administered by a dental professional using a specially designed cartridge handle. The cartridge is inserted into the handle, and the powder is expressed into the periodontal pocket. The administration process is quick and does not require local anesthesia. Patients should avoid brushing the treated area for 12 hours and abstain from using interproximal cleaning devices for 10 days.
What are the most serious risks to watch for with Arestin Microspheres 1 mg?+
The most serious risks associated with Arestin Microspheres 1 mg include allergic reactions, such as rash, itching, or swelling, and severe irritation or prolonged swelling at the application site. Patients should inform their dental professional if they experience any signs of an allergic reaction or if their symptoms worsen or do not improve.
Who should not use Arestin Microspheres 1 mg?+
Arestin Microspheres 1 mg should not be used by individuals who are allergic to minocycline or tetracyclines. It is also not recommended for use in children, pregnant women, or breastfeeding women due to the risk of tooth discoloration. Patients with weakened immune systems, such as those with HIV infections or diabetes, should consult their dental professional before using this medication.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Minocycline (Minocycline Hydrochloride)
Brand
ARESTIN MICROSPHERES
Strength
1 MG
Form
POWDER (EXTENDED RELEASE)
Route
SUBGINGIVAL
Pack size
24X1MG
Manufacturer
ORA PHARMA INC.
Origin
UNITED STATES

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