GNH USA

USA — NDC

Anzupgo 20 mg

GNH USA supplies ANZUPGO (Delgocitinib), a JAK inhibitor for chronic hand eczema. Request a quote for global supply.

Delgocitinib
ANZUPGO
CREAM
20 MG

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1
Pack/s

What is Delgocitinib?

Delgocitinib, the active ingredient in ANZUPGO, is a JAK inhibitor presented as a 20 mg/g cream for topical use. It is used to treat moderate to severe chronic hand eczema in adults who have not responded adequately to topical corticosteroids or for whom they are not advisable. GNH USA supplies ANZUPGO as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

ANZUPGO is a prescription medication specifically designed for the treatment of chronic hand eczema. It works by modulating the immune system to reduce inflammation and alleviate symptoms associated with this condition.

What is Delgocitinib used for?

ANZUPGO is a topical medication used to treat moderate to severe chronic hand eczema in adults. It is particularly beneficial for those who have not responded to other treatments or for whom topical corticosteroids are not suitable.

- Chronic hand eczema: Reduces inflammation and alleviates symptoms such as redness, itching, and irritation in the hands and wrists. - Moderate to severe cases: Effective for cases that are not well-controlled with other treatments. - Topical application: Specifically designed for use on the skin of the hands and wrists.

What are the side effects of Delgocitinib?

ANZUPGO may cause various side effects, ranging from common to serious. It is important to be aware of these potential reactions when using the medication.

Common Side Effects: - Application site reactions: Pain, tingling, itching, or redness in the area where the medicine was applied. - Skin and nail infections: Increased risk of bacterial or fungal infections in the treated area. - Low white blood cell counts: May affect the body's ability to fight infections.

Serious or Rare Side Effects: - Serious infections: Increased risk of infections such as tuberculosis, herpes zoster, and other systemic infections. - Non-melanoma skin cancer: Potential increased risk of certain types of skin cancer. - Allergic reactions: Severe allergic reactions, although rare, can occur.

What precautions apply to Delgocitinib?

When using ANZUPGO, it is important to follow certain precautions to ensure safe and effective treatment. Always consult with a healthcare provider before starting this medication.

- Inform your doctor: Tell your healthcare provider about all medical conditions, especially if you have an infection or are scheduled to receive a vaccine. - Avoid live vaccines: Do not receive live vaccines before, during, or after treatment with ANZUPGO. - Pregnancy and breastfeeding: It is not known if ANZUPGO will harm an unborn baby or pass into breast milk. Consult your healthcare provider for guidance. - Avoid other JAK inhibitors: Do not use ANZUPGO in combination with other JAK inhibitors or potent immunosuppressants. - Active infections: Do not start using ANZUPGO if you have an active, serious infection unless directed by your healthcare provider. - Store at room temperature: Keep the medication away from moisture and heat. Do not freeze.

What does Delgocitinib interact with?

ANZUPGO may interact with other medications, which can affect its effectiveness or increase the risk of side effects. It is important to be aware of these potential interactions.

Major Interactions (Avoid): - Other JAK inhibitors: Avoid using ANZUPGO in combination with other JAK inhibitors to prevent increased risk of side effects. - Potent immunosuppressants: Do not use ANZUPGO with other potent immunosuppressants to avoid compromising the immune system.

Moderate Interactions (Monitor Closely): - Vaccines: Consult your healthcare provider before receiving any vaccines while using ANZUPGO. - Other topical medications: Inform your healthcare provider about all topical medications you are using to avoid potential interactions. - Medications affecting the immune system: Monitor closely when using ANZUPGO with other medications that affect the immune system.

Frequently asked questions

What is ANZUPGO used for?+
ANZUPGO is a topical medication used to treat moderate to severe chronic hand eczema in adults. It is particularly beneficial for those who have not responded to other treatments or for whom topical corticosteroids are not suitable. The active ingredient, delgocitinib, works by modulating the immune system to reduce inflammation and alleviate symptoms associated with chronic hand eczema.
How does delgocitinib work?+
Delgocitinib works by inhibiting Janus kinase (JAK) enzymes, which play a crucial role in the body's immune response. By modulating cytokine signaling, delgocitinib reduces inflammation and helps alleviate symptoms of chronic hand eczema. This mechanism targets the underlying immune system activity that contributes to the condition.
What is the usual dose of ANZUPGO?+
The usual dose of ANZUPGO is determined by a healthcare provider. It is typically applied as a thin layer topically twice a day to the affected areas of the hands and wrists. The dosage should not exceed 30 grams per 2 weeks or 60 grams per month unless directed otherwise by a healthcare professional.
Is ANZUPGO safe during pregnancy or breastfeeding?+
It is not known if ANZUPGO will harm an unborn baby or pass into breast milk. Consult your healthcare provider for guidance if you are pregnant, planning to become pregnant, or breastfeeding. Your healthcare provider can help you weigh the potential benefits and risks of using ANZUPGO in these situations.
How do I order ANZUPGO from GNH USA?+
To order ANZUPGO from GNH USA, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will then provide pricing, availability, shipping details, and the necessary import paperwork.
How does ANZUPGO compare to other treatments for chronic hand eczema?+
ANZUPGO is a JAK inhibitor specifically designed for the treatment of moderate to severe chronic hand eczema. It is particularly beneficial for those who have not responded to other treatments or for whom topical corticosteroids are not suitable. Compared to other treatments, ANZUPGO offers a targeted approach to reducing inflammation and alleviating symptoms by modulating the immune system.
How should ANZUPGO be stored and handled?+
ANZUPGO should be stored at room temperature away from moisture and heat. Do not freeze the medication. Keep the cream in its original packaging and protect it from light. Always follow the storage instructions provided by your healthcare provider or pharmacist to ensure the medication remains effective and safe to use.
How is ANZUPGO administered?+
ANZUPGO is administered topically. Before applying the cream, wash and dry the affected areas of the hands and wrists. Apply a thin layer of the cream twice a day to the affected areas and rub it in gently. Do not use more than 30 grams per 2 weeks or 60 grams per month unless directed by your healthcare provider.
What are the most serious risks to watch for when using ANZUPGO?+
The most serious risks to watch for when using ANZUPGO include serious infections such as tuberculosis, herpes zoster, and other systemic infections. Additionally, there is a potential increased risk of non-melanoma skin cancer. It is important to monitor for signs of infection, such as a sore throat that doesn't go away, a cough that doesn't go away, fever, chills, or unusual sweating.
Who should not use ANZUPGO?+
ANZUPGO should not be used by individuals with an active, serious infection unless directed by a healthcare provider. It is also not recommended for use in combination with other JAK inhibitors or potent immunosuppressants. Additionally, individuals who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using ANZUPGO.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Delgocitinib
Brand
ANZUPGO
Strength
20 MG
Form
CREAM
Route
TOPICAL
Manufacturer
LEO PHARMA INC
Origin
CANADA

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