GNH USA

Europe — EMA

Adelone

GNH USA supplies Adelone (Prednisolone Sodium Phosphate), a glucocorticoid for inflammatory and allergic eye conditions. Request a quote for global supply.

Prednisolone Sodium Phosphate

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What is Prednisolone Sodium Phosphate?

Prednisolone sodium phosphate, the active ingredient in Adelone, is a glucocorticoid (corticosteroid) presented as a 1% (w/v) ophthalmic solution for ocular use. It is used to treat inflammatory and allergic conditions of the eye. GNH USA supplies Adelone as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Adelone is a topical corticosteroid solution designed to reduce inflammation and alleviate symptoms in various eye conditions. It is widely used in ophthalmology for its anti-inflammatory and immunosuppressive properties.

What is Prednisolone Sodium Phosphate used for?

Adelone is used to treat inflammatory and allergic conditions of the eye. It is particularly effective in managing conditions such as:

- Allergic conjunctivitis: Reduces swelling, redness, and itching caused by allergic reactions in the conjunctiva. - Uveitis: Helps in reducing inflammation in the uvea, the middle layer of the eye. - Iritis: Alleviates inflammation in the iris, the colored part of the eye. - Post-operative ocular inflammation: Used to reduce inflammation following eye surgeries. - Episcleritis: Treats inflammation of the episclera, the layer covering the sclera. - Keratitis: Reduces inflammation in the cornea, the clear front part of the eye.

What are the side effects of Prednisolone Sodium Phosphate?

Adelone may cause several side effects, ranging from common to serious. Common Side Effects: - Temporary stinging or burning upon application. - Blurred vision or increased sensitivity to light. - Mild irritation or redness of the eye. - Temporary discomfort or itching.

Serious or Rare Side Effects: - Increased intraocular pressure, which can lead to glaucoma. - Development of cataracts with prolonged use. - Secondary eye infections due to immunosuppression. - Thinning of the cornea or sclera with long-term use. - Allergic reactions, including rash or swelling around the eyes.

What precautions apply to Prednisolone Sodium Phosphate?

Adelone should be used with caution and under the supervision of a healthcare professional. Important precautions include: - Avoid prolonged use: Prolonged use can increase the risk of side effects such as glaucoma and cataracts. - Monitor for infections: Use with caution in patients with a history of eye infections. - Avoid in viral or fungal infections: Do not use in cases of viral or fungal eye infections unless under strict medical supervision. - Inform healthcare provider: Inform your healthcare provider if you have a history of glaucoma or cataracts. - Store below 25°C: Keep in the original pack, protect from light and moisture.

What does Prednisolone Sodium Phosphate interact with?

Adelone may interact with other medications, potentially altering their effects or increasing the risk of side effects. Major Interactions (Avoid): - Other corticosteroids: Concurrent use with other corticosteroids can increase the risk of side effects. - Immunosuppressants: May enhance the immunosuppressive effects, increasing the risk of infections.

Moderate Interactions (Monitor Closely): - Anticoagulants: May increase the risk of bleeding or bruising. - Antidiabetic agents: May affect blood sugar control, requiring close monitoring. - Antihypertensives: May alter blood pressure control, necessitating frequent monitoring.

Frequently asked questions

What is Adelone used for?+
Adelone is used to treat inflammatory and allergic conditions of the eye, such as allergic conjunctivitis, uveitis, iritis, and post-operative ocular inflammation. It helps reduce swelling, redness, and discomfort in the eye.
How does Prednisolone Sodium Phosphate work?+
Prednisolone sodium phosphate works by binding to intracellular glucocorticoid receptors, which then modulate gene transcription. This process suppresses the production of inflammatory cytokines and reduces the activation of immune cells, leading to a decrease in inflammation and immune response in the eye.
What is the usual dose of Adelone?+
The usual dose of Adelone is determined by a healthcare professional based on the specific condition being treated. It is typically administered as 1-2 drops in the affected eye, 3-6 times daily, depending on the severity of the condition.
Is Adelone safe during pregnancy or breastfeeding?+
The safety of Adelone during pregnancy or breastfeeding has not been fully established. It is important to consult with a healthcare provider before using Adelone if you are pregnant, planning to become pregnant, or breastfeeding.
How do I order Adelone from GNH USA?+
To order Adelone from GNH USA, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the import paperwork.
How does Adelone compare to other corticosteroids?+
Adelone is a topical corticosteroid specifically formulated for ocular use. It is similar to other corticosteroids in its anti-inflammatory and immunosuppressive effects but is designed for local application to the eye, reducing systemic side effects.
How should Adelone be stored and handled?+
Adelone should be stored below 25°C, kept in the original pack, and protected from light and moisture. It is important to avoid contamination by not touching the tip of the dropper to any surface.
How is Adelone administered?+
Adelone is administered as eye drops. The usual method involves tilting the head back, pulling down the lower eyelid to form a pouch, and instilling the prescribed number of drops into the eye. It is important to follow the healthcare provider's instructions for proper administration.
What are the most serious risks to watch for with Adelone?+
The most serious risks associated with Adelone include increased intraocular pressure, which can lead to glaucoma, and the development of cataracts with prolonged use. It is important to monitor for these conditions and consult a healthcare provider if any adverse effects are noticed.
Who should not use Adelone?+
Adelone should not be used by individuals who are allergic to prednisolone or any of its ingredients. It should also be used with caution in patients with a history of glaucoma, cataracts, or eye infections. Always consult a healthcare provider before using Adelone.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Prednisolone Sodium Phosphate
Route
Ocular Use
Manufacturer
Cooper Pharmaceuticals S.A.
Origin
EU

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