Abrysvo .06 mg/.5mL

Respiratory Syncytial Virus Vaccine, the active ingredient in Abrysvo, is a vaccine presented as a 0.06 mg/0.5 mL injection, powder, lyophilized, for solution for intramuscular use. It is indicated for the prevention of lower respiratory tract disease caused by respiratory syncytial virus (RSV) in specific populations.

GNH USA supplies Abrysvo as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Abrysvo is a vaccine designed to prevent lower respiratory tract disease (LRTD) caused by respiratory syncytial virus (RSV).

- Prevention of RSV disease in infants up to 6 months of age when administered to pregnant persons at 32–36 weeks gestation: Helps protect newborns and infants against severe LRTD caused by RSV. - Prevention of RSV disease in adults 60 years of age and older: Reduces the risk of LRTD, including severe cases, in older adults. - Prevention of RSV disease in individuals 18 through 59 years of age who are at increased risk for LRTD caused by RSV: Provides protection for individuals with higher susceptibility to RSV complications.

Abrysvo, like all vaccines, can cause side effects, although not everyone gets them.

Common Side Effects: - Fatigue: A feeling of tiredness or weakness. - Headache: Pain or discomfort in the head. - Pain at the injection site: Discomfort or soreness where the vaccine was administered. - Muscle pain: Aching or discomfort in the muscles. - Nausea: A feeling of sickness in the stomach. - Joint pain: Discomfort or soreness in the joints. - Fever: An elevated body temperature. - Chills: A feeling of coldness often accompanied by shivering.

Serious or Rare Side Effects: - Allergic reactions: Severe allergic reactions, including anaphylaxis, are rare but possible. - Guillain-Barré syndrome: A neurological disorder that can cause muscle weakness and paralysis. - Preterm birth: There is a potential risk of preterm birth when the vaccine is administered before 32 weeks of gestation.

Abrysvo should be used with caution in certain individuals to ensure safety and effectiveness.

- Allergic reactions: Do not administer Abrysvo to individuals with a history of severe allergic reactions to any component of the vaccine. - Pregnancy: Abrysvo is generally administered between 32 and 36 weeks of gestation to avoid potential risks of preterm birth. - Breastfeeding: The effects of Abrysvo while breastfeeding are not fully understood, and caution is advised. - Immunocompromised individuals: May have a diminished immune response to the vaccine. - Syncope: Procedures should be in place to avoid injury from fainting. - Storage: Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Abrysvo may interact with other medications or substances, which can affect its effectiveness or increase the risk of side effects.

Major Interactions (Avoid): - None identified: There are no major interactions that require avoidance with Abrysvo.

Moderate Interactions (Monitor Closely): - Immunosuppressive therapy: May diminish the immune response to Abrysvo. - Other vaccines: Concurrent administration with other vaccines should be carefully considered and monitored. - Allergic reactions: Individuals with a history of severe allergic reactions to vaccine components should be closely monitored.